Neurotrophic Factors

  • Gary R. Lewin
  • Bruce D. Carter

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 220)

Table of contents

  1. Front Matter
    Pages i-viii
  2. The Neurotrophin Family

    1. Front Matter
      Pages 1-1
    2. M. Bothwell
      Pages 3-15
    3. B. L. Hempstead
      Pages 17-32
    4. A. E. West, P. Pruunsild, T. Timmusk
      Pages 67-100
  3. Neurotrophin Receptors

    1. Front Matter
      Pages 101-101
    2. Katrin Deinhardt, Moses V. Chao
      Pages 103-119
    3. B. R. Kraemer, S. O. Yoon, B. D. Carter
      Pages 121-164
    4. S. Glerup, A. Nykjaer, C. B. Vaegter
      Pages 165-189
  4. The Biology of Neurotrophins

    1. Front Matter
      Pages 191-191
    2. Claire Ceni, Nicolas Unsain, Michele P. Zeinieh, Philip A. Barker
      Pages 193-221
    3. Gary R. Lewin, Stefan G. Lechner, Ewan St. John Smith
      Pages 251-282
    4. Costanza Emanueli, Marco Meloni, Wohaib Hasan, Beth A. Habecker
      Pages 309-328
  5. Neurotrophins in Pathological Conditions

    1. Front Matter
      Pages 355-355
    2. Chiara Zuccato, Elena Cattaneo
      Pages 357-409
    3. M. Sendtner
      Pages 411-441
    4. Vanessa S. Boyce, Lorne M. Mendell
      Pages 443-460
    5. E. Castrén
      Pages 461-479
  6. Back Matter
    Pages 513-520

About this book


This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles.


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Editors and affiliations

  • Gary R. Lewin
    • 1
  • Bruce D. Carter
    • 2
  1. 1.Department of NeuroscienceMax-Delbrück-Center for Molecular MedicineBerlinGermany
  2. 2.Department of BiochemistryVanderbilt University School of MedicineNashvilleUSA

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