© 2013

Multiple Origins of Sex Differences in Brain

Neuroendocrine Functions and their Pathologies

  • Donald W. Pfaff
  • Yves Christen

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Catherine Dulac, Gregg Christopher
    Pages 35-41
  3. Javier DeFelipe, Lidia Alonso-Nanclares
    Pages 43-57
  4. Francesca Ducci, Laura Bevilacqua, Paola Landi, David Goldman
    Pages 81-102
  5. James M. Swanson, Kimberly D. Lakes, Tim L. Wigal, Nora D. Volkow
    Pages 103-122
  6. Bonnie Auyeung, Simon Baron-Cohen
    Pages 123-137
  7. Phyllis M. Wise, Candice M. Brown, Jodi L. Downs
    Pages 165-178
  8. Back Matter
    Pages 179-181

About this book


In theoretical terms, sex differences in brain and behavior offer the possibility of fascinating scientific studies on a range of molecular phenomena such as DNA methylation, chromatin protein modification, non-coding DNA, resulting in important neuroanatomical and neurochemical effects. However, this general subject has been treated with much hyperbole. Historically, sex differences were assumed to be present where they did not really exist, e.g. with respect to mathematics, executive leadership, etc. etc. Under what circumstances do we really care about sex differences in brain and behavior? These circumstances concern human maladies whose diagnoses are much different between boys and girls, or between women and men. Prominent examples to be discussed today will include autism, attention deficit hyperactivity disorders and congenital adrenal hyperplasia. The meeting will end with a consideration of effects of estrogenic hormones on the injured brain, and their roles as protective agents.


attention deficit hyperactivity disorders autism chromatin modifications epigenetics fetal hormonal programming genomic imprinting

Editors and affiliations

  • Donald W. Pfaff
    • 1
  • Yves Christen
    • 2
  1. 1., Lab. of Biochem. and Molec. BiologyThe Rockefeller UniversityNew YorkUSA
  2. 2.Fondation IpsenBoulogne BillancourtFrance

Bibliographic information

  • Book Title Multiple Origins of Sex Differences in Brain
  • Book Subtitle Neuroendocrine Functions and their Pathologies
  • Editors Donald W Pfaff
    Yves Christen
  • Series Title Research and Perspectives in Endocrine Interactions
  • Series Abbreviated Title Research,Perspectives in Endocrine
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2013
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-642-33720-8
  • Softcover ISBN 978-3-662-52320-9
  • eBook ISBN 978-3-642-33721-5
  • Series ISSN 1861-2253
  • Edition Number 1
  • Number of Pages XIII, 181
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Neurosciences
    Human Genetics
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals