Antiplatelet Agents

  • Paolo Gresele
  • Gustav V. R Born
  • Carlo Patrono
  • Clive P. Page

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 210)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Pathophysiology

    1. Front Matter
      Pages 1-1
    2. Jonathan N. Thon, Joseph E. Italiano
      Pages 3-22
    3. Alexandre Kauskot, Marc F. Hoylaerts
      Pages 23-57
    4. Timothy J. Stalker, Debra K. Newman, Peisong Ma, Kenneth M. Wannemacher, Lawrence F. Brass
      Pages 59-85
    5. Philip G. de Groot, Rolf T. Urbanus, Mark Roest
      Pages 87-110
    6. Christian Schulz, Steffen Massberg
      Pages 111-133
  3. Pharmacology

    1. Front Matter
      Pages 135-135
    2. Carlo Patrono, Bianca Rocca
      Pages 137-164
    3. Isabell Bernlochner, Dirk Sibbing
      Pages 165-198
    4. Karen M. Hook, Joel S. Bennett
      Pages 199-223
    5. Matthew T. Rondina, Andrew S. Weyrich
      Pages 225-238
    6. Giovanni Davì, Francesca Santilli, Natale Vazzana
      Pages 261-286
    7. Hans Deckmyn, Simon F. De Meyer, Katleen Broos, Karen Vanhoorelbeke
      Pages 311-337
    8. Kathleen Freson, Chris Van Geet
      Pages 369-394
    9. Giovanni de Gaetano, Iolanda Santimone, Francesco Gianfagna, Licia Iacoviello, Chiara Cerletti
      Pages 395-434
    10. Leonard C. Edelstein, Paul F. Bray
      Pages 435-445
    11. Richard Amison, Clive Page, Simon Pitchford
      Pages 447-468
  4. Therapy

    1. Front Matter
      Pages 469-469
    2. Christopher H. May, A. Michael Lincoff
      Pages 495-518
    3. Ralph Weber, Johannes Brenck, Hans-Christoph Diener
      Pages 519-546
    4. Francesco Violi, Stefania Basili, Jeffrey S. Berger, William R. Hiatt
      Pages 547-563
  5. Back Matter
    Pages 607-616

About this book


Antiplatelet therapy is the cornerstone of treatment of ischemic cardiovascular disease and over the last few years spectacular advancements in this field have been recorded. This is the first comprehensive handbook entirely dedicated to all the aspects of antiplatelet therapy. The book is divided into three main sections, pathophysiology, pharmacology and therapy, for a total of 23 chapters. A large group of leading experts from different European countries and from the USA, both from academia and industry, have contributed to the book. Besides a detailed overview on the pharmacology and clinical applications of all the currently used or of the novel antiplatelet agents, innovative approaches (e.g. intracellular signalling as an antiplatelet target, small RNAs as platelet therapeutics, etc.) or unconventional aspects (e.g. pharmacologic modulation of the inflammatory action of platelets are also treated. The book is oriented to both basic investigators and to clinicians involved with research on platelet inhibition or with the clinical use of antiplatelet therapies.


Antithrombotic Therapy Atherothrombosis Cardiovascular Disease Inflammation Platelet Pathophysiology

Editors and affiliations

  • Paolo Gresele
    • 1
  • Gustav V. R Born
    • 2
  • Carlo Patrono
    • 3
  • Clive P. Page
    • 4
  1. 1., Department of Internal MedicineUniversity of PerugiaPerugiaItaly
  2. 2.InstituteThe William Harvey ResearchLondonUnited Kingdom
  3. 3.Istituto di FarmacologiaUniversità Cattolica del S. CuoreRomaItaly
  4. 4.King's College LondonSackler Inst. Pulmonary PharmacologyLondonUnited Kingdom

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