Transactions on Large-Scale Data- and Knowledge-Centered Systems IV

Special Issue on Database Systems for Biomedical Applications

  • Abdelkader Hameurlain
  • Josef Küng
  • Roland Wagner
  • Christian Böhm
  • Johann Eder
  • Claudia Plant

Part of the Lecture Notes in Computer Science book series (LNCS, volume 6990)

Table of contents

  1. Front Matter
  2. Database Systems for Biomedical Applications

    1. Philipp L. Rautenberg, Andrey Sobolev, Andreas V. M. Herz, Thomas Wachtler
      Pages 1-14
    2. João Zamite, Fabrício A. B. Silva, Francisco Couto, Mário J. Silva
      Pages 40-72
    3. Idir Amine Amarouche, Djamal Benslimane, Mahmoud Barhamgi, Michael Mrissa, Zaia Alimazighi
      Pages 95-123
    4. Paola Bonfante, Francesca Cordero, Stefano Ghignone, Dino Ienco, Luisa Lanfranco, Giorgio Leonardi et al.
      Pages 124-147
    5. Andreas Dander, Michael Handler, Michael Netzer, Bernhard Pfeifer, Michael Seger, Christian Baumgartner
      Pages 148-157
    6. Imen Bouraoui, Salim Chitroub, Ahmed Bouridane
      Pages 188-208
  3. Back Matter

About this book


The LNCS journal Transactions on Large-Scale Data- and Knowledge-Centered Systems focuses on data management, knowledge discovery, and knowledge processing, which are core and hot topics in computer science. Since the 1990s, the Internet has become the main driving force behind application development in all domains. An increase in the demand for resource sharing across different sites connected through networks has led to an evolution of data- and knowledge-management systems from centralized systems to decentralized systems enabling large-scale distributed applications providing high scalability. Current decentralized systems still focus on data and knowledge as their main resource. Feasibility of these systems relies basically on P2P (peer-to-peer) techniques and the support of agent systems with scaling and decentralized control. Synergy between Grids, P2P systems, and agent technologies is the key to data- and knowledge-centered systems in large-scale environments.

This special issue of Transactions on Large-Scale Data- and Knowledge-Centered Systems highlights some of the major challenges emerging from the biomedical applications that are currently inspiring and promoting database research. These include the management, organization, and integration of massive amounts of heterogeneous data; the semantic gap between high-level research questions and low-level data; and privacy and efficiency. The contributions cover a large variety of biological and medical applications, including genome-wide association studies, epidemic research, and neuroscience.


bioinformatics data mining knowledge discovery in databases semantic annotation statistical methods

Editors and affiliations

  • Abdelkader Hameurlain
    • 1
  • Josef Küng
    • 2
  • Roland Wagner
    • 2
  • Christian Böhm
    • 3
  • Johann Eder
    • 4
  • Claudia Plant
    • 5
  1. 1.Institut de Recherche en Informatique de Toulouse (IRIT)Paul Sabatier UniversityToulouse CedexFrance
  2. 2.University of Linz, FAWLinzAustria
  3. 3.Department of Computer ScienceLudwig-Maximilians-UniversitätMünchenGermany
  4. 4.Institut für Informatik-SystemeAlpen Adria Universität KlagenfurtKlagenfurtAustria
  5. 5.Department of Scientific ComputingFlorida State UniversityTallahasseeUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag GmbH Berlin Heidelberg 2011
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Computer Science Computer Science (R0)
  • Print ISBN 978-3-642-23739-3
  • Online ISBN 978-3-642-23740-9
  • Series Print ISSN 0302-9743
  • Series Online ISSN 1611-3349
  • Buy this book on publisher's site
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