© 2012

Morphogenesis and Pathogenicity in Fungi

  • José Pérez Martín
  • Antonio Di Pietro

Part of the Topics in Current Genetics book series (TCG, volume 22)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Steven D. Harris
    Pages 1-20
  3. Alexandra Brand, Neil A. R. Gow
    Pages 21-41
  4. André Fleißner
    Pages 43-59
  5. Elena Pérez-Nadales, Antonio Di Pietro
    Pages 61-79
  6. Carlos R. Vázquez de Aldana, Jaime Correa-Bordes
    Pages 81-96
  7. Martine Bassilana, Peter Follette
    Pages 133-161
  8. Iran Malavazi, Gustavo Henrique Goldman
    Pages 163-196
  9. Elizabeth R. Ballou, J. Andrew Alspaugh, Connie B. Nichols
    Pages 197-223
  10. Julia Schumacher, Paul Tudzynski
    Pages 225-241
  11. Barry Scott, Yvonne Becker, Matthias Becker, Gemma Cartwright
    Pages 243-264
  12. Asfia Qureshi, Maurizio Del Poeta
    Pages 265-280
  13. Back Matter
    Pages 281-286

About this book


Infectious fungal diseases continue to take their toll in terms of human suffering and enormous economic losses. Invasive infections by opportunistic fungal pathogens are a major cause of morbidity and mortality in immuno-compromised individuals. At the same time, plant pathogenic fungi have devastating effects on crop production and human health. New strategies for antifungal control are required to meet the challenges posed by these agents, and such approaches can only be developed through the identification of novel biochemical and molecular targets. However, in contrast to bacterial pathogens, fungi display a wealth of “lifestyles” and modes of infection. This diversity makes it extremely difficult to identify individual, evolutionarily conserved virulence determinants and represents a major stumbling block in the search for common antifungal targets. In order to activate the infection programme, all fungal pathogens must undergo appropriate developmental transitions that involve cellular differentiation and the introduction of a new morphogenetic programme. How growth, cell cycle progression and morphogenesis are co-ordinately regulated during development has been an active area of research in fungal model systems such as budding and fission yeast. By contrast, we have only limited knowledge of how these developmental processes shape fungal pathogenicity, or of the role of the cell cycle and morphogenesis regulators as true virulence factors. This book combines state-of-the-art expertise from diverse pathogen model systems to update our current understanding of the regulation of fungal morphogenesis as a key determinant of pathogenicity in fungi.



Antifungal control Fungal diseases Fungal morphogenesis Fungal pathogens

Editors and affiliations

  • José Pérez Martín
    • 1
  • Antonio Di Pietro
    • 2
  1. 1.Centro Nacional de Biotecnología, Depto. Biotecnología MicrobianaCSIC MadridMadridSpain
  2. 2., Department of GeneticsUniversity of CordobaCordobaSpain

Bibliographic information

Industry Sectors
Health & Hospitals


From the reviews:

“This book describes the molecular basis of morphogenesis and pathogenicity in the fungi and highlights new approaches. … All the chapters are well organized and each chapter contains an introduction at the beginning and a conclusion at the last that can be very useful for the reader. … This book is very important to scientists, researchers and teachers as well as students who are interested in fungal morphogenesis and pathogenicity. Therefore this book should be available in all schools, research laboratories, community and university libraries.” (Kasun M. Thambugala, Fungal Diversity, Vol. 57 (1), November, 2012)