Prevention of Bone Metastases

  • Markus Joerger
  • Michael Gnant

Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 192)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Geertje van der Horst, Gabri van der Pluijm
    Pages 1-31
  3. Daniele Santini, Francesco Pantano, Bruno Vincenzi, Giuseppe Tonini, Francesco Bertoldo
    Pages 33-64
  4. Michael Gnant, Peter Dubsky, Peyman Hadji
    Pages 65-91
  5. Lynn Decoster, Filippo de Marinis, Kostas Syrigos, Vera Hirsh, Kristiaan Nackaerts
    Pages 93-108
  6. Fred Saad, Jean-Baptiste Lattouf
    Pages 109-126
  7. G. J. Morgan, Ping Wu
    Pages 127-143
  8. Daniele Santini, Maria Elisabetta Fratto, Matti Aapro
    Pages 171-185
  9. Markus Joerger, Jens Huober
    Pages 197-223

About this book


Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with breast, lung, and prostate cancer and disease progression in cases of multiple myeloma.  The combined use of bisphosphonates and cytostatics is also discussed, with a report on first clinical data.  Further topics addressed include the significance of the bone microenvironment, special issues in the elderly patient, the use of bone turnover markers, and initial findings obtained with denosumab.


Bisphosphonates Bone metastases Breast cancer Prostate cancer Zoledronic acid

Editors and affiliations

  • Markus Joerger
    • 1
  • Michael Gnant
    • 2
  1. 1., Dept. of Medical OncologyKantonsspital St. GallenSt. GallenSwitzerland
  2. 2.Chirurgische Klinik, Abt. Allgemeine ChirurgieUniversitätsklinikum WienWienAustria

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2012
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-642-21891-0
  • Online ISBN 978-3-642-21892-7
  • Series Print ISSN 0080-0015
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology