Biofilms and Veterinary Medicine

  • Steven Percival
  • Derek Knottenbelt
  • Christine Cochrane

Part of the Springer Series on Biofilms book series (BIOFILMS, volume 6)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Steven L. Percival, Jerry S. Knapp, David W. Williams, John Heritage, Lucy A. Brunton
    Pages 1-39
  3. Steven L. Percival, Sladjana Malic, Helena Cruz, David W. Williams
    Pages 41-68
  4. Ana B. García, Steven L. Percival
    Pages 69-110
  5. Alice J. Gardner, Steven L. Percival, Christine A. Cochrane
    Pages 111-128
  6. David W. Williams, Michael A. O. Lewis, Steven L. Percival, Tomoari Kuriyama, Sónia da Silva, Marcello P. Riggio
    Pages 129-142
  7. Samantha J. Westgate, Steven L. Percival, Peter D. Clegg, Derek C. Knottenbelt, Christine A. Cochrane
    Pages 143-173
  8. Peter D. Clegg
    Pages 175-190
  9. Samuel J. Hooper, Steven L. Percival, Christine A. Cochrane, David W. Williams
    Pages 191-203
  10. Marielle B. Melchior
    Pages 205-221
  11. Back Matter
    Pages 253-257

About this book

Introduction

Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis.  However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds.  Their existence explains many of the enigmas of microbial infection and a better grasp of the process may well serve to establish a different approach to infection control and management.   Biofilms and their associated complications have been found to be involved in up to 80% of all infections.  A large number of studies targeted at the bacterial biofilms have been conducted, and many of them are referred to in this book, which is the first of its kind.   These clinical observations emphasize the importance of biofilm formation to both superficial and systemic infections, and the inability of current antimicrobial therapies to ‘cure’ the resulting diseases even when the in vitro tests suggest that they should be fully effective.

In veterinary medicine the concept of biofilms and their role in the pathogenesis of disease has lagged seriously behind that in human medicine.  This is all the more extraordinary when one considers that much of the research has been carried out using veterinary species in experimental situations.   The clinical features of biofilms in human medicine is certainly mimicked in the veterinary species but there is an inherent and highly regrettable indifference to the failure of antimicrobial therapy in many veterinary disease situations, and this is probably at its most retrograde in veterinary wound management. 

Biofilms and Veterinary Medicine is specifically focused on discussing the concerns of biofilms to health and disease in animals and provides a definitive text for veterinary practitioners, medical and veterinary students, and researchers.

Keywords

antibiotic resistance biofilms medicine veterinary medicine zoonotic infections

Editors and affiliations

  • Steven Percival
    • 1
  • Derek Knottenbelt
    • 2
  • Christine Cochrane
    • 3
  1. 1.Chester, CheshireUnited Kingdom
  2. 2.School of Veterinary Science, Equine Hospital, LeahurstUniversity of LiverpoolNestonUnited Kingdom
  3. 3.School of Veterinary Science, Equine Hospital, LeahurstUniversity of LiverpoolNestonUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-21289-5
  • Copyright Information Springer-Verlag Berlin Heidelberg 2011
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-21288-8
  • Online ISBN 978-3-642-21289-5
  • Series Print ISSN 1863-9607
  • Series Online ISSN 1863-9615
  • About this book
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