Molecular Biomineralization

Aquatic Organisms Forming Extraordinary Materials

  • Werner E. G. Müller

Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 52)

Also part of the Marine Molecular Biotechnology book sub series (MMB, volume 52)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Metallic Biominerals

    1. Front Matter
      Pages 1-1
    2. Jens Baumgartner, Damien Faivre
      Pages 3-27
    3. Loes E. Bevers, Elizabeth C. Theil
      Pages 29-47
    4. P. P. Sujith, P. A. Loka Bharathi
      Pages 49-76
    5. Xiaohong Wang, Matthias Wiens, Heinz C. Schröder, Ute Schloßmacher, Werner E. G. Müller
      Pages 77-110
  3. Biocalcium

    1. Front Matter
      Pages 111-111
    2. Brunella Perito, Giorgio Mastromei
      Pages 113-139
    3. Qingling Feng
      Pages 141-197
    4. P. U. P. A. Gilbert, Fred H. Wilt
      Pages 199-223
    5. Valeria Matranga, Rosa Bonaventura, Caterina Costa, Konstantinos Karakostis, Annalisa Pinsino, Roberta Russo et al.
      Pages 225-248
  4. Biosilica – and its Application

    1. Front Matter
      Pages 249-249
    2. Werner E. G. Müller, Xiaohong Wang, Ailin Chen, Shixue Hu, Lu Gan, Heinz C. Schröder et al.
      Pages 251-281
    3. Heinz C. Schröder, Matthias Wiens, Xiaohong Wang, Ute Schloßmacher, Werner E. G. Müller
      Pages 283-312
  5. Nacre

    1. Front Matter
      Pages 313-313
    2. Li-ping Xie, Fang-jie Zhu, Yu-juan Zhou, Chao Yang, Rong-qing Zhang
      Pages 331-352
    3. Frédéric Marin, Prabakaran Narayanappa, Sébastien Motreuil
      Pages 353-395
  6. Back Matter
    Pages 397-403

About this book


The concept of ‘biomineralization’ signifies mineralization processes that take place in close association with organic molecules or matrices. The awareness that mineral formation can be guided by organic molecules notably contributed to the understanding of the formation of the inorganic skeletons of living organisms. Modern electron microscopic and spectroscopic analyses have successfully demonstrated the participation of biological systems in several mineralization processes, and prominent examples include the formation of bio-silica in diatoms and sponges. This insight has already made the application of recombinant technology for the production of valuable inorganic polymers, such as bio-silica, possible. This polymer can be formed by silicatein under conditions that cannot be matched by chemical means. Similarly, the efforts described in this book have elucidated that certain organisms, bacteria in deep-sea polymetallic nodules and coccoliths in seamount crusts, are involved in the deposition of marine minerals. Strategies have already been developed to utilize such microorganisms for the biosynthesis and bioleaching of marine deposits. Moreover, studies reveal that bio-polymers enhance the hydroxyapatite formation of bone-forming cells and alter the expression of important regulators of bone resorption, suggesting a potential for bone regeneration and treatment / prevention of osteoporosis.


Bio-silica Biocalcification Biomaterials Biomineralization Crustaceans Echinoderms Osteoporosis Porifera

Editors and affiliations

  • Werner E. G. Müller
    • 1
  1. 1.Inst. Physiologische Chemie, Abt. Angewandte MolekularbiologieUniversität MainzMainzGermany

Bibliographic information