© 2004

Phosphoinositides in Subcellular Targeting and Enzyme Activation

  • Harald Stenmark

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 282)

Table of contents

  1. Front Matter
    Pages i-ix
  2. R. J. Botelho, C. C. Scott, S. Grinstein
    Pages 1-30
  3. G. E. Cozier, J. Carlton, D. Bouyoucef, P. J. Cullen
    Pages 49-88
  4. H. C. G. Birkeland, H. Stenmark
    Pages 89-115
  5. P. Hilpelä, M. K. Vartiainen, P. Lappalainen
    Pages 117-163
  6. M. O. Hannigan, C. K. Huang, D. Q. Wu
    Pages 165-175
  7. G. Hammond, C. L. Thomas, G. Schiavo
    Pages 177-206
  8. Back Matter
    Pages 207-212

About this book



The reversible recruitment of intracellular protein complexes to membranes is essential for immune cell functions, including chemotaxis, phagocytosis and signalling. Such recruitment is often controlled by phosphorylated derivatives of phosphatidylinositol, known as phosphoinositides. These lipids also serve to activate enzyme systems that carry out complex reactions such as chromatin remodelling and pre-mRNA procesing. This issue of Current Topics in Microbiology and Immunology presents an overview of how phosphoinositides function in protein recruitment and enzyme activation and presents physiologically important examples of protein-phosphoinositide interactions.


chemotaxis endocytosis microorganism phagocytosis phosphoinositide protein proteins signal transduction

Editors and affiliations

  • Harald Stenmark
    • 1
  1. 1.Department of BiochemistryThe Norwegian Radium HospitalOsloNorway

Bibliographic information

  • Book Title Phosphoinositides in Subcellular Targeting and Enzyme Activation
  • Editors Harald Stenmark
  • Series Title Current Topics in Microbiology and Immunology
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2004
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-3-540-00950-4
  • Softcover ISBN 978-3-642-62299-1
  • eBook ISBN 978-3-642-18805-3
  • Series ISSN 0070-217X
  • Edition Number 1
  • Number of Pages IX, 209
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Immunology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals


From the reviews:

"The book consists of seven chapters that focus on the various functions of PtdIns. … summarises recent advances in the burgeoning field of inositol lipids and provides a snapshot of where the field stands in 2003. The field is moving rapidly but this volume will be a useful addition for many researchers who have only recently discovered that their favourite protein is regulated by PtdIns." (Shamshad Cockcroft, nature cell biology, Vol. 6 (6), June, 2004)