Effect-Directed Analysis of Complex Environmental Contamination

  • Werner Brack

Part of the The Handbook of Environmental Chemistry book series (HEC, volume 15)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Werner Brack, Nadin Ulrich, Mahmoud Bataineh
    Pages 83-118
  3. Pim E. G. Leonards, Rikke Brix, Damià Barceló, Marja Lamoree
    Pages 143-165
  4. Emma Schymanski, Tobias Schulze, Jos Hermans, Werner Brack
    Pages 167-198
  5. John L. Durant, Arthur L. Lafleur
    Pages 199-235
  6. Corine J. Houtman, Juliette Legler, Kevin Thomas
    Pages 237-265
  7. Mechthild Schmitt-Jansen, Peter C. von der Ohe, Stephanie Franz, Stefanie Rotter, Sergi Sabater, Dick de Zwart et al.
    Pages 315-339
  8. Back Matter
    Pages 341-345

About this book


Today more than 5 million chemicals are known and roughly 100,000 of them are frequently used, with both numbers rising. Many of these chemicals are ultimately released into the environment and may cause adverse effects to ecosystems and human health. Effect-directed analysis (EDA) is a promising tool for identifying predominant toxicants in complex, mostly environmental mixtures combining effect testing, fractionation and chemical analysis. In the present book leading experts in the field provide an overview of relevant approaches and tools used in EDA. This includes diagnostic biological tools, separation techniques and advanced analytical and computer tools for toxicant identification and structure elucidation. Examples of the successful application of EDA are discussed such as the identification of mutagens in airborne particles and sediments, of endocrine disruptors in aquatic ecosystems and of major toxicants in pulp and paper mill effluents. This book is a valuable, comprehensive and interdisciplinary source of information for environmental scientists and environmental agencies dealing with the analysis, monitoring and assessment of environmental contamination.


carcinogens effect-directed analysis endocrine disruptors environmental toxicology mutagens toxicants

Editors and affiliations

  • Werner Brack
    • 1
  1. 1.for Environmental Research, Department of Effect-Directed AnalysisUFZ Helmholtz CentreLeipzigGermany

Bibliographic information

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