Active Implants and Scaffolds for Tissue Regeneration

  • Meital Zilberman

Part of the Studies in Mechanobiology, Tissue Engineering and Biomaterials book series (SMTEB, volume 8)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Jonathan J. Elsner, Israela Berdicevsky, Adaya Shefy-Peleg, Meital Zilberman
    Pages 3-37
  3. Boaz Mizrahi, Christopher Weldon, Daniel S. Kohane
    Pages 39-56
  4. Mădălina V. Natu, Hermínio C. de Sousa, Maria H. Gil
    Pages 57-85
  5. Dennis Douroumis, Ichioma Onyesom
    Pages 87-125
  6. Mikael Trollsas, Bozena Maslanka, Nam Pham, Qing Lin, Syed Hossainy, Shaw Ling Hsu et al.
    Pages 127-143
  7. Morten Østergaard Andersen, Jørgen Kjems
    Pages 145-165
  8. John Igwe, Ami Amini, Paiyz Mikael, Cato Laurencin, Syam Nukavarapu
    Pages 169-192
  9. Aysen Tezcaner, Dilek Keskin
    Pages 193-223
  10. Rossella Dorati, Claudia Colonna, Ida Genta, Bice Conti
    Pages 259-285
  11. Emil Ruvinov, Smadar Cohen
    Pages 289-328
  12. Dae-Duk Kim, Dong-Hwan Kim, Yun-Jeong Son
    Pages 329-349
  13. Ali Demir Sezer, Erdal Cevher
    Pages 377-406
  14. Maya Davidovich-Pinhas, Havazelet Bianco-Peled
    Pages 439-456
  15. Yu Tang, Mayura Oak, Rhishikesh Mandke, Buddhadev Layek, Gitanjali Sharma, Jagdish Singh
    Pages 457-479
  16. Darren Svirskis, Bryon E. Wright, Jadranka Travas-Sejdic, Sanjay Garg
    Pages 481-512
  17. Back Matter
    Pages 513-514

About this book


Active implants are drug or protein-eluting implants that induce healing effects, in addition to their regular task, for example support. This effect is achieved by controlled release of bioactive agents to the surrounding tissue. This book presents a broad overview of biomaterial platforms used in internal and external drug-eluting implants. The book is divided into four parts:
1. Drug-eluting implants
2. Scaffolds for bone regeneration
3. Scaffolds based on natural polymers
4. New polymeric systems for active implants
The 18 reviews describe active implants in terms of matrix formats, incorporated drugs and their release profiles from the implants, as well as cell-implant interactions and functions. The effect of the process parameters on the micro or nano-structure and on the resulting drug release profiles, mechanical and physical properties, and other relevant properties, are emphasized.  It is the first book to describe a broad range of active implants and present the frontier of knowledge in this field. The new biomaterial approaches for active implants described in this book enhance the tools available for clinically important biomedical applications.


antipoliferative agent drug implants drug-eluting vascular crafts protein-eluting implants smart polymeric systems wound dressings

Editors and affiliations

  • Meital Zilberman
    • 1
  1. 1.Fac. Engineering, Dept. Biomedical EngineeringTel Aviv UniversityTel AvivIsrael

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2011
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Engineering Engineering (R0)
  • Print ISBN 978-3-642-18064-4
  • Online ISBN 978-3-642-18065-1
  • Series Print ISSN 1868-2006
  • Series Online ISSN 1868-2014
  • Buy this book on publisher's site
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