• Bertil B. Fredholm

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 200)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Bertil B. Fredholm
    Pages 1-9
  3. Hiroshi Ashihara, Misako Kato, Alan Crozier
    Pages 11-31
  4. Sharron H. Francis, Konjeti R. Sekhar, Hengming Ke, Jackie D. Corbin
    Pages 93-133
  5. Serge Guerreiro, Marc Marien, Patrick P. Michel
    Pages 135-150
  6. Christa E. Müller, Kenneth A. Jacobson
    Pages 151-199
  7. Hendrik Jan Smit
    Pages 201-234
  8. Detlev Boison
    Pages 251-266
  9. Jana Sawynok
    Pages 311-329
  10. Tarja Porkka-Heiskanen
    Pages 331-348
  11. Alba Minelli, Ilaria Bellezza
    Pages 349-372
  12. Hartmut Osswald, Jürgen Schnermann
    Pages 391-412
  13. Niels P. Riksen, Paul Smits, Gerard A. Rongen
    Pages 413-437
  14. Stephen L. Tilley
    Pages 439-456
  15. György Haskó, Bruce Cronstein
    Pages 457-468
  16. Akio Ohta, Michail Sitkovsky
    Pages 469-481
  17. Marie-Soleil Beaudoin, Terry E. Graham
    Pages 509-548
  18. Back Matter
    Pages 549-559

About this book


In the present volume of the Handbook of Experimental Pharmacology well known experts describe the actions of different xanthines with a focus on caffeine and theophylline. A special chapter is devoted to theobromine, an active component of chocolate, the actions of which are less well characterized. This book also presents the pharmacology of one xanthine derivative, propentofylline, as an example of a xanthine that has gone through extensive development for a novel therapeutic area.


Adenosine Caffeine Methylxanthines Phosphodiesterase Theophylline

Authors and affiliations

  • Bertil B. Fredholm
    • 1
  1. 1.Dept. Physiology & PharmacologyKarolinska InstituteStockholmSweden

Bibliographic information

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