© 2010

Chiral Recognition in Separation Methods

Mechanisms and Applications

  • Alain Berthod

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Chunlei Wang, Ping Sun, Daniel W. Armstrong
    Pages 77-96
  3. Alain Berthod, Hai Xiao Qiu, Sergey M. Staroverov, Mikhail A. Kuznestov, Daniel W. Armstrong
    Pages 203-222
  4. Timothy J. Ward, Aprile Gilmore, Karen Ward, Courtney Vowell
    Pages 223-240
  5. Min Li, David K. Bwambok, Sayo O. Fakayode, Isiah M. Warner
    Pages 289-329
  6. Back Matter
    Pages 331-337

About this book


The importance of chiral interactions for both preparative and analytical separations, particularly for pharmaceutical applications, is underlined by numerous publications in this field. Here, for the first time, a team of experienced analysts from industry and academe presents a comprehensive review of the various mechanisms that result in enantiomer separations. A better understanding of these processes is crucial for setting as well as improving chiral separation procedures and also for developing new applications. The coverage in this book includes a range of separation methods, such as gas, liquid, or countercurrent chromatography, and capillary electrophoresis. The special case of chiral ionic liquids is examined in detail. Most modern chiral selectors are discussed, including derivatized polysaccharide- and cyclodextrin-based selectors, along with a newly introduced class of carbohydrates: the cyclofructose selectors. This publication will be required reading not only for research and development departments in the pharmaceutical and cosmetic industries, but also for researchers in toxicology, environmental monitoring, and food research.


Chiral Ionic Liquids Chiral Selection Chiral Selectors Chromatography Liquid Chromatography Polysaccharide-Based Selectors amines chromium development environment environmental monitoring food pharmaceutical research toxicology

Editors and affiliations

  • Alain Berthod
    • 1
  1. 1., CNRS UMR 5180University of LyonVilleurbanne CédexFrance

Bibliographic information

Industry Sectors
Chemical Manufacturing


From the reviews:

“I strongly recommend this book to those interested in understanding the mechanisms responsible for chiral recognition in chromatographic and electrophoretic techniques. … This book may be of interest both to beginners and to confirmed practitioners in the field. … Chiral recognition in separation methods is a valuable book compiling a detailed description of most of the essential chiral selectors employed in chromatographic and electrophoretic techniques. … Both students and practitioners interested in enantiorecognition mechanisms should have it in their library.” (Caroline West, Analytical and Bioanalytical Chemistry, Vol. 400, 2011)