© 2010

RNA Technologies and Their Applications

  • Volker A. Erdmann
  • Jan Barciszewski


  • RNA mediated gene silencing is a powerful technology to downregulate the expression of targeted genes within the cell.

  • Now RNA interference based therapeutics is to be released.

  • This book provides a state-of-the-art review concerning the molecular basis as well as applications of RNA based technologies in molecular biology and medicine.

  • These topics are covered by 19 contributions written by internationally respected experts in the field of RNA Technologies.


Part of the RNA Technologies book series (RNATECHN)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Kuniaki Saito, Keita Miyoshi, Mikiko C. Siomi, Haruhiko Siomi
    Pages 1-28
  3. Sandra D. Laufer, Anke Detzer, Georg Sczakiel, Tobias Restle
    Pages 29-58
  4. Xiaoping Yi, Rui Lu
    Pages 59-92
  5. Mitsutoshi Nakada, Daisuke Kita, Yutaka Hayashi, Kazuyuki Kawakami, Jun-ichiro Hamada, Toshinari Minamoto
    Pages 107-129
  6. Yu Zhang, Robert M. Friedlander
    Pages 131-160
  7. Philippe Sarret, Louis Doré-Savard, Pascal Tétreault, Valérie Bégin-Lavallée, Nicolas Beaudet
    Pages 161-190
  8. Karin J. von Eije, Ben Berkhout
    Pages 191-208
  9. Vickram Ramkumar, Debashree Mukherjea, Sarvesh Jajoo, Tejbeer Kaur, Leonard P. Rybak
    Pages 209-226
  10. Hsiang Ho, Jayavani Aruri, Safoora Ahmed, Anand K. Ganesan
    Pages 227-253
  11. Stephen I. Rudnick, Veenu Aishwarya, Alan M. Gewirtz
    Pages 255-275
  12. Marianne Farnebo, Klas G. Wiman
    Pages 277-284
  13. Doreen Kunze, Kai Kraemer, Susanne Fuessel
    Pages 285-303
  14. Stefanie Grund, Sven Diederichs
    Pages 325-354
  15. Jun Liu, Guoku Hu, Rui Zhou, Kristen M. Drescher, Xian-Ming Chen
    Pages 355-367
  16. Maciej Szymański, Jan Barciszewski
    Pages 393-418
  17. Nahalie Berteaux, Nathalie Spruyt, Eric Adriaenssens
    Pages 419-443

About this book


RNA technologies are the driving forces of modern medicine and biotechnology. They combine the fields of biochemistry, chemistry, molecular biology, cell biology, physics, nanotechnology and bioinformatics. The combination of these topics is set to revolutionize the medicine of tomorrow. After more than 15 years of extensive research in the field of RNA technologies, the first therapeutics are ready to reach the first patients. Thus we are witnessing the birth of a very exciting time in the development of molecular medicine, which will be based on the methods of RNA technologies. This volume is the first of a series. It covers various aspects of RNA interference and microRNAs, although antisense RNA applications, hammerhead ribozyme structure and function as well as non-coding RNAs are also discussed. The authors are internationally highly respected experts in the field of RNA technologies


Translation biochemistry bioinformatics biology gene expression genes regulation

Editors and affiliations

  • Volker A. Erdmann
    • 1
  • Jan Barciszewski
    • 2
  1. 1.Inst. Chemie und BiochemieFU BerlinBerlinGermany
  2. 2.Inst. Bioorganic ChemistryPAN PoznanPoznanPoland

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