Transactions on Computational Systems Biology XII

Special Issue on Modeling Methodologies

  • Corrado Priami
  • Rainer Breitling
  • David Gilbert
  • Monika Heiner
  • Adelinde M. Uhrmacher

Part of the Lecture Notes in Computer Science book series (LNCS, volume 5945)

Also part of the Lecture Notes in Bioinformatics book sub series (volume 5945)

Table of contents

  1. Front Matter
  2. Rainer Breitling, Robin A. Donaldson, David R. Gilbert, Monika Heiner
    Pages 1-12
  3. Mathias John, Cédric Lhoussaine, Joachim Niehren, Adelinde M. Uhrmacher
    Pages 13-76
  4. Michael Pedersen, Gordon D. Plotkin
    Pages 77-145
  5. Antje Beyer, Peter Thomason, Xinzhong Li, James Scott, Jasmin Fisher
    Pages 146-162
  6. Roberto Larcher, Corrado Priami, Alessandro Romanel
    Pages 163-198
  7. Céline Kuttler, Cédric Lhoussaine, Mirabelle Nebut
    Pages 199-228
  8. Federica Ciocchetta, Andrea Degasperi, John K. Heath, Jane Hillston
    Pages 229-262
  9. Back Matter

About this book


The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena.

This special issue of the journal focuses on the topic of modeling methodologies. It starts with a position paper by the guest editors, entitled Biomodel Engineering - from Structure to Behavior, which is followed by the technical contributions covering a broad range of modeling methodologies. Two papers focus on new modeling languages, and these are followed by an article presenting a case study demonstrating the value of the qualitative network approach. With the remaining three contributions, the special issue leaves the area of qualitative modeling, to move toward quantitative programming with the BlenX language and the application of more theoretical process calculi.


biochemical systems design brane calculus cell signalling coloured Petri nets combinatorial explosion computational biology computational modeling continuous time Markov chains differential equations gene expression large-scale metabolic pathwa modeling tar

Editors and affiliations

  • Corrado Priami
    • 1
  • Rainer Breitling
    • 2
  • David Gilbert
    • 3
  • Monika Heiner
    • 4
  • Adelinde M. Uhrmacher
    • 5
  1. 1.Centre for Computational and Systems BiologyThe Microsoft Research - University of TrentoPovo (TN)Italy
  2. 2.Groningen BioinformaticsUniversity of GroningenHarenThe Netherlands
  3. 3.School of Information SystemsBrunel UniversityUxbridgeUK
  4. 4.Computer Science InstituteBrandenburg University of TechnologyCottbusGermany
  5. 5.Institute of Computer ScienceUniversity of RostockRostockGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2010
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Computer Science
  • Print ISBN 978-3-642-11711-4
  • Online ISBN 978-3-642-11712-1
  • Series Print ISSN 0302-9743
  • Series Online ISSN 1611-3349
  • Buy this book on publisher's site
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