Inflammation and Gastrointestinal Cancers

  • Janusz A. Z.¬†Jankowski

Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 185)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Stephen G. Maher, John V. Reynolds
    Pages 1-34
  3. Shane Duggan, David Prichard, Murat Kirca, Dermot Kelleher
    Pages 35-50
  4. Adam Humphries, Trevor A. Graham, Stuart A. C. McDonald
    Pages 51-63
  5. Anna Nicholson, Janusz Jankowski
    Pages 65-82
  6. Michael Rathbone, Barrie Rathbone
    Pages 83-97
  7. Noor Jawad, Natalie Direkze, Simon J. Leedham
    Pages 99-115
  8. Piotr Milkiewicz, Ewa Wunsch
    Pages 117-133
  9. Malcolm R. Alison, Linda J. Nicholson, Wey-Ran Lin
    Pages 135-148
  10. K. L. Yim, D. Cunningham
    Pages 159-171
  11. Gaius Longcroft-Wheaton, Pradeep Bhandari
    Pages 185-199

About this book


Inflammation in gastrointestinal mucosa can remodel the topography of the overlying epithelium. If such inflammation is chronic, it has fundamental clinical consequences, the principal of which is premalignant metaplasia throughout the alimentary tract. Furthermore, mucosal inflammation, even if subtle, is the single most common pathway for GI cancer.

This book discusses all aspects of the relation between inflammation and GI cancer, from the basic science through to the translational science which is helping in the optimization of clinical management strategies. Among the topics considered are the impact of inherited syndromes; the roles of acid reflux, H. pylori, inflammatory bowel disease, and primary sclerosing cholangitis; screening strategies; targeted drug therapies; genetics; and the use of endoscopic methods. The authors are the best in their field, and this book is designed for the enthusiastic student as well as the professional in GI science and medicine.


Colon cancer Esophageal cancer Gastric cancer Inflammatory bowel disease Liver cancer Mucosal inflammation Primary sclerosing cholangitis Targeted therapies

Editors and affiliations

  • Janusz A. Z.¬†Jankowski
    • 1
  1. 1.Leicester Royal Infirmary, Dept. Cancer Studies andUniversity of LeicesterLeicesterUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2011
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-642-03502-9
  • Online ISBN 978-3-642-03503-6
  • Series Print ISSN 0080-0015
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology