© 2009

Optical Sensor Systems in Biotechnology

  • Govind Rao
  • Covers trends in modern biotechnology

  • All aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science, are treated

  • More information as well as the electronic version available at


Part of the Advances in Biochemical Engineering/Biotechnology book series (ABE, volume 116)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. K. Ray, M. H. Chowdhury, J. Zhang, Y. Fu, H. Szmacinski, K. Nowaczyk et al.
    Pages 1-28
  3. João G. Henriques, Stefan Buziol, Elena Stocker, Arthur Voogd, José C. Menezes
    Pages 29-72
  4. Guido Rudolph, Patrick Lindner, Arne Bluma, Klaus Joeris, Geovanni Martinez, Bernd Hitzmann et al.
    Pages 73-97
  5. Hung Lam, Yordan Kostov
    Pages 125-142
  6. Kenneth F. Reardon, Zhong Zhong, Kevin L. Lear
    Pages 143-157
  7. Back Matter
    Pages 159-161

About this book


Of all things natural, light is the most sublime. From the very existential belief of the origins of the universe to its role in the evolution of life on earth, light has been inextricably woven into every aspect of our lives. I am grateful to Springer-Verlag and Thomas Scheper for this invitation to organize this volume that continues to expand the use of light to create next generation sensing applications. Indeed, the very act of expanding the frontiers of learning and knowledge are referred to in many languages and cultures as enlightenment. Early optical instruments relied largely on simple combinations of mirrors, prisms and lenses. With these simple devices, substantial progress was made in our understanding of the properties of light and of its interactions with matter. Things got more complicated with the evolution of optical instruments in labo- tory use. Early systems used bulky and expensive hardware to generate light, split it into the desired wavelengths and finally collect it for analysis. The discovery of the laser pushed the technology further, but did not do much to make its adoption more widespread as the lasers themselves were large and required substantial el- trical power to operate. The true revolution is just beginning. Advances in mic- electronics have resulted in the possibility of truly low-cost (using the consumer electronics industry as a parallel) devices that exploit optical measurement technology.


Biosensor antibody biosensors biotechnology cell protein sensors spectroscopy

Editors and affiliations

  • Govind Rao
    • 1
  1. 1.Center for Advanced Sensor Technology and Department of Chemical and Biochemical EngineeringUniversity of Maryland Baltimore CountyBaltimoreUSA

Bibliographic information

Industry Sectors
Chemical Manufacturing
Consumer Packaged Goods


From the reviews:

“Optical Sensor Systems in Biotechnology contains six chapters by different authors covering topics ranging from optical principles and set-ups to real-world applications of optical sensor systems. … this book shows the great potential of new optical methods in this field. … give a very good overview of the topic addressed and show that optical sensors are used in different applications and can be very valuable in biotechnology. … Valuable information on the different topics is easily accessed … .” (Florian Pröll, Analytical and Bioanalytical Chemistry, Vol. 399, 2011)