© 2009

Applied Physiology in Intensive Care Medicine

  • Göran Hedenstierna
  • Jordi Mancebo
  • Laurent Brochard
  • Michael R. Pinsky

Table of contents

  1. Front Matter
    Pages 1-13
  2. Physiological Notes

    1. Front Matter
      Pages 1-2
    2. Belen Cabello, Jordi Mancebo
      Pages 11-14
    3. Evans R. Fernández-Pérez, Rolf D. Hubmayr
      Pages 15-16
    4. Claude Guerin, Jean-Christophe Richard
      Pages 17-20
    5. U. Lucangelo, L. Blanch
      Pages 25-28
    6. Enrico Calzia, Peter Radermacher
      Pages 37-40
    7. Robert Rodríguez-Roisin, Josep Roca
      Pages 41-43
    8. Amal Jubran
      Pages 45-48
    9. Andreas Bacher
      Pages 49-52
    10. Frank Bloos, Konrad Reinhart
      Pages 53-55
    11. Jerome Aboab, Bruno Louis, Bjorn Jonson, Laurent Brochard
      Pages 57-60
    12. Michael R. Pinsky
      Pages 69-72

About this book


In theory, treatment decisions and assessments of response to therapy in critically ill patients should usually be based on measures of physiological function. Nevertheless, the most appropriate use of the information embodied in such measures is often unclear, and rarely supported by prospective clinical trials. In reality, the bedside clinician is therefore forced to rely primarily on physiological principles when deciding upon the best treatment. Unfortunately, however, the necessary knowledge base of the clinician is often less than optimal for the purpose, and habit or prior training may be more influential than science.

Against this background, this second, revised edition of Applied Physiology in Intensive Care Medicine aims to help overcome the fundamental unevenness in clinicians’ understanding of applied physiology. It is divided into three sections. The first comprises a series of "physiological notes" that concisely and clearly capture the essence of the physiological perspectives underpinning our understanding of disease and response to therapy. The second section contains more detailed associated reviews on measurement techniques and physiological processes, while the third provides a number of seminal studies on diverse topics in intensive care.

This up-to-date compendium of practical bedside knowledge essential to the effective delivery of acute care medicine has been written by some of the most renowned experts in the field. It will serve the clinician as an invaluable reference source on key issues regularly confronted in everyday practice.


Acute Care Medicine Applied Physiology COPD Critical Care Medicine Hemodynamic monitoring Renal Physiology Respirator Sepsis Trauma arterial pressure cardiovascular intensive care medicine

Editors and affiliations

  • Göran Hedenstierna
  • Jordi Mancebo
  • Laurent Brochard
  • Michael R. Pinsky

There are no affiliations available

Bibliographic information

Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


From the reviews of the second edition:

"This is a collection of physiologic papers from reviews presented in Intensive Care Medicine from 2002 to early 2009. Presentations from major figures in clinical critical care physiology are collected. Teachers, practitioners, and senior trainees are an appropriate audience for this work … . Presentations are clear … with excellent figures. … Of the approximately 15 new reviews added to this edition, the majority of the new work comes in the discussion of physiologic processes … . recommend it for physiology pertinent to the ICU." (David J. Dries, Doody’s Review Service, October, 2009)

“A compendium of the physiologic notes published between 2002 and 2009 in Intensive Care Medicine with the associated review articles. For intensive care physicians.” (Pediatric Endocrinology Reviews, Vol. 7 (2), December, 2009)