© 2009

Engineering of Stem Cells

  • Ulrich Martin


  • Covers trends in modern biotechnology

  • All aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science, are treated

  • More information as well as the electronic version available at


Part of the Advances in Biochemical Engineering / Biotechnology book series (ABE, volume 114)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Martine Geraerts, Catherine M. Verfaillie
    Pages 1-21
  3. Andreas Bosio, Volker Huppert, Susan Donath, Petra Hennemann, Michaela Malchow, Uwe A. O. Heinlein
    Pages 23-72
  4. Ina Gruh, Ulrich Martin
    Pages 73-106
  5. Jun Wu, Faquan Zeng, Richard D. Weisel, Ren-Ke Li
    Pages 107-128
  6. Michal Amit, Joseph Itskovitz-Eldor
    Pages 173-184
  7. Shoukhrat Mitalipov, Don Wolf
    Pages 185-199
  8. Back Matter
    Pages 237-239

About this book


I am very pleased to present this volume on engineering stem cells in Advances in Biochemical Engineering and Biotechnology. This volume stays abreast of recent developments in stem cell biology and the high expectations concerning the dev- opment of stem cell based regenerative therapies. Regenerative medicine is the focus of current biomedical research, with unique challenges related to scientific, technical and ethical issues of stem cell research, and the potential added value of connecting biomedicine with enabling techno- gies such as materials sciences, mechanical- and nano-engineering. Research activities in regenerative medicine include strategies in endogenous regeneration of injured or degenerated tissues by means of gene therapy or cell transplantation, as well as complex approaches to replace or reconstruct lost or malformed tissue structures, by applying tissue engineering approaches. In most cases, the speci- ized functional cell types of interest cannot be isolated from the diseased organ or expanded to a sufficient degree, and various stem and progenitor cell types rep- sent the only applicable cell source. In almost all cases, stem cells have to be engineered, sometimes for functional improvement, in many cases to produce large numbers of cells, and frequently to achieve efficient and specific differentiation in the cell type(s) of interest.


Tissue Engineering biochemical engineering biochemistry biomedicine biotechnology cell biology cells chemistry gene therapy regenerative medicine tissue

Editors and affiliations

  • Ulrich Martin
    • 1
  1. 1.Leibnitz Res.Lab.Biotechnol.Hannover Medical SchoolHannoverGermany

Bibliographic information

  • Book Title Engineering of Stem Cells
  • Editors Ulrich Martin
  • Series Title Advances in Biochemical Engineering / Biotechnology
  • Series Abbreviated Title Advs Biochem.Engineering
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2009
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Chemistry and Materials Science Chemistry and Material Science (R0)
  • Hardcover ISBN 978-3-540-88805-5
  • Softcover ISBN 978-3-642-26091-9
  • eBook ISBN 978-3-540-88806-2
  • Series ISSN 0724-6145
  • Series E-ISSN 1616-8542
  • Edition Number 1
  • Number of Pages XIII, 239
  • Number of Illustrations 18 b/w illustrations, 8 illustrations in colour
  • Topics Biotechnology
    Biochemistry, general
    Molecular Medicine
  • Buy this book on publisher's site
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