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Molecular Biology of Neuropsychiatric Disorders

  • Dieter B. Wildenauer

Part of the Nucleic Acids and Molecular Biology book series (NUCLEIC, volume 23)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Dieter B. Wildenauer, Diah Mutiara B. Wildenauer, Sibylle G. Schwab
    Pages 51-79
  3. Sabine M Klauck
    Pages 81-98
  4. Virginia L. Misener, Cathy L. Barr
    Pages 99-164
  5. Steven P. Hamilton
    Pages 165-185
  6. Sibylle G Schwab, Adrian Scott, Dieter B Wildenauer
    Pages 187-204
  7. Brigitta Bondy, Peter Zill
    Pages 205-227
  8. Giuseppe Verdile, Ralph N. Martin
    Pages 229-276
  9. Abbas Parsian, Biswanath Patra
    Pages 277-289
  10. Back Matter
    Pages 291-294

About this book

Introduction

It is generally accepted that neuropsychiatric disorders have a biological basis. Pathological changes leading to illness have been confirmed for Alzheimer’s (amyloid plaques) and Parkinson’s disease (loss of dopaminergic transmission) and are the foundation for studies on the molecular biology of these disorders. For other neuropsychiatric disorders, in particular for schizophrenic and affective disorders, molecular causes appear to be more complex and therefore remain hypothetical, despite decades of research. Changes in a number of neuronal pathways and structures have been reported to be associated with these disorders and are currently under extensive investigation. The present volume reviews recent knowledge with emphasis on ongoing research findings. Current hypotheses based on these findings are described and discussed.

Knowing the molecular basis of these disorders is not only of academic interest, but is essential for:

• identifying risk factors contributing to the development of the disorders,

• detecting biomarkers which will aid in diagnosis,

• providing new and specific targets for development of causal pharmacological

treatment.

Keywords

Alzheimer Alzheimer´s disease Neuronal Pathways Parkinson Parkinson´s Disease Psychiatric Disorders attention deficit hyperactivity disorder (ADHD) autism spectrum disorder diagnosis genetics mood disorder neurobiology psychiatric disorder

Editors and affiliations

  • Dieter B. Wildenauer
    • 1
  1. 1.Center for Clinical Research in Neuropsychiatry (CCRN)Graylands HospitalClaremontAustralia

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-540-85383-1
  • Copyright Information Springer Berlin Heidelberg 2009
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-540-85382-4
  • Online ISBN 978-3-540-85383-1
  • Series Print ISSN 0933-1891
  • Buy this book on publisher's site
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