© 2009

Antiviral Strategies

  • Hans-Georg Kräusslich
  • Ralf Bartenschlager

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 189)

Table of contents

  1. Front Matter
    Pages i-xi
  2. B. Müller, Hans-Georg Kräusslich
    Pages 1-24
  3. Raymond F. Schinazi, Steven J. Coats, Leda C. Bassit, Johan Lennerstrand, James H. Nettles, Selwyn J. Hurwitz
    Pages 25-51
  4. E. De Clercq, J. Neyts
    Pages 53-84
  5. Jeffrey Anderson, Celia Schiffer, Sook-Kyung Lee, Ronald Swanstrom
    Pages 85-110
  6. Mark von Itzstein, Robin Thomson
    Pages 111-154
  7. H. Zimmermann, G. Hewlett, H. Rübsamen-Waigmann
    Pages 155-176
  8. Tom Melby, Mike Westby
    Pages 177-202
  9. Stéphane Chevaliez, Jean-Michel Pawlotsky
    Pages 203-241
  10. D. Laer, C. Baum, U. Protzer
    Pages 265-297
  11. S. Fleßa, P. Marschall
    Pages 347-374
  12. Back Matter
    Pages 375-379

About this book


A crucial issue for antiviral therapy is the fact that all antiviral substances rapidly select for resistance; thus, monitoring and overcoming resistance has become a most important clinical paradigm of antiviral therapy. This calls for cautious use of antiviral drugs and implementation of combination therapies. In parallel, efforts in drug discovery have to be continued to develop compounds with novel mode-of-action and activity against resistant strains. This book reviews the current status of antiviral therapy, from the roads to development of new compounds to their clinical use and cost effectiveness. Individual chapters address in more detail all available drug classes and outline new approaches currently under development.


Antiviral Drug DNA Drug Resistance HIV/Aids Hepatitis Influenza Interferon Virus gene therapy genes infection infections viral infection

Editors and affiliations

  • Hans-Georg Kräusslich
    • 1
  • Ralf Bartenschlager
    • 1
  1. 1.Hygiene Institute Department of VirologyUniversitätsklinikum HeidelbergHeidelbergGermany

Bibliographic information

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