© 2008

Optical Coherence Tomography

Technology and Applications

  • Wolfgang Drexler
  • James G. Fujimoto

Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)

Table of contents

  1. Front Matter
    Pages I-XXIX
  2. Optical Coherence Tomography Technology

    1. J. Fujimoto, W. Drexler
      Pages 1-45
    2. J. A. Izatt, M. A. Choma
      Pages 47-72
    3. P. E. Andersen, T. M. Jørgensen, L. Thrane, A. Tycho, H. T. Yura
      Pages 73-115
    4. B. E. Bouma, G. J. Tearney, B. J. Vakoc, S. H. Yun
      Pages 209-237
    5. W. Drexler, Y. Chen, A. Aguirre, B. Považay, A. Unterhuber, J. G. Fujimoto
      Pages 239-279
    6. V. R. Shidlovski
      Pages 281-299
    7. A. Unterhuber, B. Považay, A. Aguirre, Y. Chen, F. X. Kärtner, J. G. Fujimoto et al.
      Pages 301-358
    8. S. H. Yun, B. E. Bouma
      Pages 359-377
    9. Z. Hu, A. M. Rollins
      Pages 379-404
    10. D. L. Marks, T. S. Ralston, S. A. Boppart
      Pages 405-426
  3. En Face Optical Coherence Tomography and Optical Coherence Microscopy

    1. G. Hüttmann, P. Koch, R. Birngruber
      Pages 429-445
    2. R. B. Rosen, P. Garcia, A. Gh. Podoleanu, R. Cucu, G. Dobre, M. E. J. van Velthoven et al.
      Pages 447-474
    3. C. K. Hitzenberger, M. Pircher
      Pages 475-503
    4. A. D. Aguirre, J. G. Fujimoto
      Pages 505-542
    5. Z. Chen, S. Tang
      Pages 543-563
    6. A. Dubois, A. C. Boccara
      Pages 565-591

About this book


Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is emerging as a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. A new generation OCT technology has now been developed, representing a quantum leap in resolution and speed, achieving in vivo optical biopsy, i.e. the visualization of tissue architectural morphology in situ and in real time. Functional extensions of OCT technology enable non-invasive, depth resolved functional assessment and imaging of tissue. These new techniques should not only improve image contrast, but should also enable the differentiation of pathologies via metabolic properties or functional state. The book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from biomedical and clinical perspectives. The chapters are written by leading international research groups, in a style comprehensible to a broad audience. It will be of interest not only to physicists, scientists and engineers, but also to biomedical and clinical researchers from different medical specialties.


Biomedical engineering Image Processing Imaging/radiology Medicine Ophthalmology optical coherence tomography tissue engineering ultrasound

Editors and affiliations

  • Wolfgang Drexler
    • 1
  • James G. Fujimoto
    • 2
  1. 1.School of Optometry and Vision SciencesCardiff UniversityCardiffUK
  2. 2.Department of Electrical Engineering and Computer ScienceMassachusetts Institute of TechnologyCambridgeUSA

Bibliographic information

Industry Sectors
Health & Hospitals


From the reviews:

"This is a comprehensive review of the current status of optical coherence tomography (OCT) technology and its applications in the medical field. … The authors are the leading experts in this field and as such are able to use a unique approach for targeting physicists, scientists, engineers, and researchers in medical specialties, along with practitioners. The book is also suitable for graduate students and residents interested in pursuing an education in medical specialties." (Paul Gueye, Doody’s Review Service, June, 2009)