© 2008

Molecular Imaging I

  • Wolfhard Semmler
  • Markus Schwaiger

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 185/1)

Table of contents

  1. Front Matter
    Pages i-xxvii
  2. Instrumentation

    1. Ralf B. Schulz, Wolfhard Semmler
      Pages 3-22
    2. Marc Kachelrieß
      Pages 23-52
    3. Virginia C. Spanoudaki, Sibylle I. Ziegler
      Pages 53-74
    4. Tobias Schaeffter, Hannes Dahnke
      Pages 75-90
    5. Peter Hauff, Michael Reinhardt, Stuart Foster
      Pages 91-107
    6. Bernd J. Pichler, Martin S. Judenhofer, Christina Pfannenberg
      Pages 109-132
  3. Imaging Probes

    1. Carmen Burtea, Sophie Laurent, Luce Vander Elst, Robert N. Muller
      Pages 135-165
    2. Kai Licha, Michael Schirner, Gavin Henry
      Pages 203-222
    3. Peter Hauff, Michael Reinhardt, Stuart Foster
      Pages 223-245
    4. Silvio Aime, Walter Dastrù, Roberto Gobetto, Daniela Santelia, Alessandra Viale
      Pages 247-272
  4. Back Matter
    Pages 273-280

About this book


The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is being addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.


Magnetic Resonance Molecular Imaging PET/CT computed tomography (CT) positron emission tomography ultrasound

Editors and affiliations

  • Wolfhard Semmler
    • 1
  • Markus Schwaiger
    • 2
  1. 1.Forschungsschwerpunkt Innovative Krebsdiagnostik und -therapie (E)Deutsches KrebsforschungszentrumHeidelbergGermany
  2. 2.Nuklearmedizinische Klinik und PoliklinikKlinikum rechts des Isar des Technischen Universität MünchenMünchenGermany

Bibliographic information

Industry Sectors
Health & Hospitals
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From the reviews:

“Topics covered are intended for a sophisticated multidisciplinary audience. … serves as an introduction to the expansive field of molecular imaging while developing in the reader an understanding of many of the complexities that allow novel approaches to studying the physiology, biochemistry, and molecular biology of intact living systems. … imaging scientists and clinicians who wish to learn more about the most advanced methods and applications of their craft should benefit from the coverage of the topics laid out in this book.” (Geoffrey D. Clarke, Radiology, Vol. 256 (1), July, 2010)