Molecular Microbiology of Heavy Metals

  • Editors
  • Dietrich H. Nies
  • Simon Silver

Part of the Microbiology Monographs book series (MICROMONO, volume 6)

Table of contents

  1. Front Matter
    Pages I-VIII
  2. Molecular Physiology of Metal-Microbe Interactions According to Mechanisms

    1. Front Matter
      Pages 1-2
    2. Stephen Tottey, Duncan R. Harvie, Nigel J. Robinson
      Pages 3-35
    3. John D. Helmann, Sumarin Soonsanga, Scott Gabriel
      Pages 37-71
    4. Jon L. Hobman, Kaneyoshi Yamamoto, Taku Oshima
      Pages 73-115
    5. Dietrich H. Nies
      Pages 117-142
    6. Hauke Harms
      Pages 143-157
    7. Dirk Wesenberg, Corinna Bleuel, Gerd-Joachim Krauss
      Pages 159-186
  3. Molecular Physiology of Metal-Microbe Interactions According to Groups

    1. Front Matter
      Pages 187-188
    2. Volkmar Braun, Klaus Hantke
      Pages 189-219
    3. Gregor Grass
      Pages 221-233
    4. Krisztina M. Papp-Wallace, Andrea S. Moomaw, Michael E. Maguire
      Pages 235-257
    5. David Magnani, Marc Solioz
      Pages 259-285
    6. Robert P. Hausinger, Deborah B. Zamble
      Pages 287-320
    7. Christopher Rensing, Bharati Mitra
      Pages 321-341
    8. Sylvia Franke
      Pages 343-355
    9. Hiranmoy Bhattacharjee, Barry P. Rosen
      Pages 371-406
    10. Carlos Cervantes, Jesús Campos-García
      Pages 407-419
    11. Guenter Schwarz, Peter-Leon Hagedoorn, Katrin Fischer
      Pages 421-451
  4. Back Matter
    Pages 453-460

About this book


All forms of life depend on a variety of heavy metal ions. Nearly one-third of all gene products require a metal ion for proper folding or function. However, even metals generally regarded as non-poisonous are toxic at higher concentrations, including the essential ones. Thus, sensitive regulation of metal uptake, storage, allocation and detoxification is needed to maintain cellular homeostasis of heavy metal ions.

Molecular Microbiology of Heavy Metals includes chapters on allocation of metals in cells, metal transporter, storage and metalloregulatory proteins, cellular responses to metal ion stress, transcription of genes involved in metal ion homeostasis, uptake of essential metals, metal efflux and other detoxification mechanisms. Also discussed are metal bioreporters for the nanomolar range of concentration and tools to address the metallome. Chapters in the second part cover specific metals such as Fe, Mn, Cu, Ni, Co, Zn and Mo as key nutrient elements and Ag, As, Cd, Hg and Cr as toxic elements.


Bioinorganic chemisty Biometals Biosensors Inorganic metabolism Metal ion homeostasis Metalloproteins enzymes genes metabolism physiology proteins transcription

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2007
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-540-69770-1
  • Online ISBN 978-3-540-69771-8
  • Series Print ISSN 1862-5576
  • Buy this book on publisher's site
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