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Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials

Techniques and Applications

  • Book
  • © 2007

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Editors:
  1. Ling Qin

    1. Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China

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  2. Harry K. Genant

    1. University of California, San Francisco
      Synarc, Inc, USA

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  3. James F. Griffith

    1. Department of Radiology and Organ Imaging, The Chinese University of Hong Kong, Hong Kong SAR, China

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  4. Kwok Sui Leung

    1. Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China

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  • Introduction of cutting-edge bioimaging technologies for studying musculoskeletal systems
  • Application of advanced imaging techniques
  • Richly illustrated with 2-D and 3-D images of the related organs or tissues
  • Includes supplementary material: sn.pub/extras

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Table of contents (43 chapters)

  1. Perspectives of Advances in Musculoskeletal and Scaffold Biomaterial Imaging Technologies and Applications

    1. Advances in Scaffold Biomaterial Research and Applications

      1. Application of Nano-CT and High-Resolution Micro-CT to Study Bone Quality and Ultrastructure, Scaffold Biomaterials and Vascular Networks
        • Phil L. Salmon, Alexander Y. Sasov
        Pages 323-331
      2. Bio-imaging Technologies in Studying Bone-Biomaterial Interface: Applications in Experimental Spinal Fusion Model
        • Chun Wai Chan, Jack Chun-Yiu Cheng, Hiu-Yan Yeung, Ling Qin
        Pages 333-351
      3. Assessment of Bone, Cartilage, Tendon and Bone Cells by Confocal Laser Scanning Microscopy
        • Chris W. Jones, Kirk H. M. Yip, Jiake Xu, Ming-Hao Zheng
        Pages 353-367

  2. Specific Applications of Advances in Musculoskeletal and Scaffold Biomaterial Imaging Technologies

    1. Front Matter

      Pages 369-369
      Download chapter PDF

    2. In Assessment of Osteoporosis and Treatment

      1. TEM Study of Bone and Scaffold Materials
        • Shu-Xin Qu, Xiong Lu, Yang Leng
        Pages 373-392
      2. Material and Structural Basis of Bone Fragility: A Rational Approach to Therapy
        • Ego Seeman
        Pages 393-398
      3. Application of Micro-CT and MRI in Clinical and Preclinical Studies of Osteoporosis and Related Disorders
        • Ye-Bin Jiang, Jon Jacobson, Harry K. Genant, Jenny Zhao
        Pages 399-415
      4. CT-Based Microstructure Analysis for Assessment of Bone Fragility
        • Masako Ito
        Pages 417-429
      5. Discrimination of Contributing Factors to Bone Fragility Using vQCT In Vivo
        • Margarita Meta, Ying Lu, Joyce H. Keyak, Thomas F. Lang
        Pages 431-449
      6. Osteoporosis Research with the vivaCT40
        • Jürg A. Gasser, Peter Ingold
        Pages 451-462
      7. Mechanical Properties of Vertebral Trabeculae with Ageing Evaluated with Micro-CT
        • He Gong, Ming Zhang, Ling Qin
        Pages 463-473
      8. MRI Evaluation of Osteoporosis
        • James Francis Griffith
        Pages 475-484
      9. Multiple Bio-imaging Modalities in Evaluation of Epimedium-Derived Phytoestrogenic Fraction for Prevention of Postmenopausal Osteoporosis
        • Ge Zhang, Ling Qin, Yin-Yu Shi
        Pages 485-504
      10. Areal and Volumetric Bone Densitometry in Evaluation of Tai Chi Chuan Exercise for Prevention of Postmenopausal Osteoporosis
        • Pauline Po-Yee Lui, Ling Qin, Wing-Yin Choi, Kai-Ming Chan
        Pages 505-515
      11. Enhancement of Osteoporotic Bone Using Injectable Hydroxyapatite in OVX Goats Evaluated by Multi-imaging Modalities
        • Wing-Hoi Cheung, Ling Qin, Kam-Fai Tam, Wing-Sum Siu, Kwok-Sui Leung
        Pages 517-527

    3. In Assessment of Fracture Repair

      1. Quality of Healing Compared Between Osteoporotic Fracture and Normal Traumatic Fracture
        • Ke-Rong Dai, Yong-Qiang Hao
        Pages 531-541
      2. Monitoring Fracture Healing Using Digital Radiographies
        • Gang Li, Mark Murnaghan
        Pages 543-552
      3. Fracture Callus Under Anti-resorptive Agent Treatment Evaluated by pQCT
        • Yong-Ping Cao, Satoshi Mori, Tasuku Mashiba, Michael S. Westmore, Linda Ma
        Pages 553-566

    4. In Assessment of Osteonecrosis

      1. Volumetric Measurement of Osteonecrotic Femoral Head Using Computerized MRI and Prediction For Its Mechanical Properties
        • Zi-Rong Li, Zhen-Cai Shi
        Pages 569-577
      2. Biomedical Engineering in Surgical Repair of Osteonecrosis: the Role of Imaging Technology
        • Shi-Bi Lu, Jiang Peng, Ai-Yuan Wang, Ming-Xue Sun, Jie-Mo Tian, Li-Min Dong
        Pages 579-591
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Keywords

About this book

This book provides a perspective on the current status of bioimaging technologies developed to assess the quality of musculoskeletal tissue with an emphasis on bone and cartilage. It offers evaluations of scaffold biomaterials developed for enhancing the repair of musculoskeletal tissues. These bioimaging techniques include micro-CT, nano-CT, pQCT/QCT, MRI, and ultrasound, which provide not only 2-D and 3-D images of the related organs or tissues, but also quantifications of the relevant parameters. The advance bioimaging technologies developed for the above applications are also extended by incorporating imaging contrast-enhancement materials. Thus, this book will provide a unique platform for multidisciplinary collaborations in education and joint R&D among various professions, including biomedical engineering, biomaterials, and basic and clinical medicine.

Editors and Affiliations

  • Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China

    Ling Qin, Kwok Sui Leung

  • University of California, San Francisco

    Harry K. Genant

  • Synarc, Inc, USA

    Harry K. Genant

  • Department of Radiology and Organ Imaging, The Chinese University of Hong Kong, Hong Kong SAR, China

    James F. Griffith

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