Atlas of Ulcers in Systemic Sclerosis

Diagnosis and Management

  • Marco Matucci-Cerinic
  • Christopher P. Denton

Table of contents

  1. Front Matter
    Pages i-xi
  2. Definition and Classification

    1. Front Matter
      Pages 1-1
    2. Daniel E. Furst, Yossra Atef Suliman, Christopher P. Denton, Marco Matucci-Cerinic
      Pages 3-5
    3. Carina Gaertner, Oana-Diana Persa, Nicolas Hunzelmann
      Pages 7-13
  3. Pathobiology of Digital Ulcers

    1. Front Matter
      Pages 25-25
    2. Janine Schniering, Britta Maurer, Oliver Distler
      Pages 27-37
  4. Microvascular Modifications and Ulcers

    1. Front Matter
      Pages 43-43
    2. Michael Hughes, Marina E. Anderson, Ariane L. Herrick
      Pages 45-62
    3. Maurizio Cutolo, Alberto Sulli, Vanessa Smith
      Pages 63-78
  5. Complications

    1. Front Matter
      Pages 87-87
    2. Guya Piemonte, Francesca Braschi, Laura Rasero
      Pages 89-94
    3. Silvia Bellando-Randone, Gemma Lepri
      Pages 95-98
    4. Felice Galluccio
      Pages 105-107
    5. Paul Legendre, Luc Mouthon
      Pages 109-113
    6. Francesca Bartoli, Laura Cometi, Marco Matucci-Cerinic
      Pages 115-118
  6. General Approach to Digital Ulceration: Algorithm

    1. Front Matter
      Pages 119-119
    2. Cosimo Bruni, Tiziana Pucci, Laura Rasero, Christopher P. Denton
      Pages 121-123
    3. Yannick Allanore
      Pages 125-129
  7. Differential Diagnosis

    1. Front Matter
      Pages 131-131
  8. The Local Treatment of Skin Ulcers in Systemic Sclerosis

    1. Front Matter
      Pages 143-143
    2. Guya Piemonte, Laura Benelli, Francesca Braschi, Laura Rasero
      Pages 145-159
    3. Silvia Bellando-Randone, Tiziana Pucci, Laura Rasero, Christopher P. Denton, Marco Matucci-Cerinic
      Pages 161-164
  9. The Systemic Treatment of Skin Ulcers in Systemic Sclerosis

    1. Front Matter
      Pages 165-165
    2. Cosimo Bruni, Silvia Bellando-Randone, Christopher P. Denton, Marco Matucci-Cerinic
      Pages 167-171
    3. Lindsay Muir, Ariane L. Herrick
      Pages 173-182
    4. Jasmin Raja, Voon H. Ong
      Pages 183-192
    5. Nabil George, Todd Kanzara, Kuntal Chakravarty
      Pages 193-205
  10. Future Strategies: Regenerative Medicine

    1. Front Matter
      Pages 207-207
    2. Nicoletta Del Papa, Eleonora Zaccara, Gabriele Di Luca, Wanda Maglione
      Pages 209-215
  11. Atlas

    1. Front Matter
      Pages 217-217
    2. Marco Matucci-Cerinic, Christopher P. Denton, Tiziana Pucci, Francesca Braschi, Claudia Fantauzzo, Lucia Paganelli
      Pages 219-231
  12. Back Matter
    Pages 233-238

About this book


This Atlas examines skin ulcers in patients affected by systemic sclerosis. Although they are not life threatening, digital ulcers cause enormous pain, impact function and quality of life, and can lead to serious local complications such as gangrene, osteomyelitis, and permanent tissue loss. Knowledge and understanding of these ulcers is pivotal in everyday practice in order to arrive at an accurate early diagnosis, a correct analysis of ulcer characteristics, and an appropriate direct and systematic treatment. To that end, this book describes all the major characteristics of skin ulcers in systematic sclerosis, including classification, evaluation, and categorization. Richly illustrated for practical use, Atlas of Ulcers in Systemic Sclerosis: Diagnosis and Management is an essential resource for physicians and related professionals, residents, and graduate students in rheumatology, dermatology, and angiology.


Digital lesion Scleroderma Skin ulcer Systematic sclerosis ulcer

Editors and affiliations

  • Marco Matucci-Cerinic
    • 1
  • Christopher P. Denton
    • 2
  1. 1.Department of Experimental and Clinical MedicineUniversity of FlorenceFlorenceItaly
  2. 2.Division of MedicineUniversity College London, Centre for Rheumatology, Royal Free HospitalLondonUK

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-98475-9
  • Online ISBN 978-3-319-98477-3
  • Buy this book on publisher's site
Industry Sectors