Autophagy in Health and Disease

Potential Therapeutic Approaches

  • Kursad Turksen

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Kai Li, Zhuo Yang
    Pages 1-20
  3. Shalmoli Bhattacharyya, Ajay Kumar
    Pages 21-29
  4. Ralph A. Zirngibl, Irina Voronov
    Pages 71-85
  5. Yasunao Numata, Daisuke Hirayama, Kohei Wagatsuma, Tomoya Iida, Hiroshi Nakase
    Pages 87-100
  6. Toshihiko Aki, Kanako Noritake, Kana Unuma, Koichi Uemura
    Pages 101-118
  7. Vladislav Volarevic, Jelena Jakovljevic, C. Randall Harrell, Crissy Fellabaum, Nebojsa Arsenijevic
    Pages 119-133
  8. José A. Boga, Zulema Pérez-Martínez, Ana Coto-Montes, Marta E. Alvarez-Argüelles, Russel J. Reiter
    Pages 153-161
  9. Bakiye Goker Bagca, Cigir Biray Avci
    Pages 163-177

About this book


This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases. 

The chapters cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson's, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and 'bench to bedside'. Chapters are contributed by leading authorities and describe the general concepts of autophagy in health and disease, marrying cell biology and pharmacology and covering: studies derived from preclinical experiments, manufacturing considerations,and regulatory requirements pertaining to drug discovery and manufacturing and production. This volume will be useful for basic scientists as well as already practicing clinicians and advanced graduate students.


Aging Diabetes Mitochondria Neurodegeneration Osteoarthritis

Editors and affiliations

  • Kursad Turksen
    • 1
  1. 1.OttawaCanada

Bibliographic information