Genomic Applications in Pathology

  • George Jabboure Netto
  • Karen L. Kaul

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Genomic Technologies

    1. Front Matter
      Pages 1-1
    2. Matthew W. Anderson
      Pages 29-39
    3. Jacquelyn Reuther, Angshumoy Roy, Federico A. Monzon
      Pages 41-63
    4. Cornelia Braicu, Diana Gulei, Beatriz de Melo Maia, Ioana Berindan-Neagoe, George A. Calin
      Pages 65-92
    5. Dorraya El-Ashry, Marija Balic, Richard J. Cote
      Pages 93-110
    6. Natasha B. Hunter, Julia A. Beaver, Ben Ho Park
      Pages 111-125
  3. Practice-Related Aspects of Clinical Genomics

    1. Front Matter
      Pages 127-127
    2. Richard L. Haspel
      Pages 129-140
    3. Roger D. Klein
      Pages 159-169
    4. Henry T. Greely
      Pages 171-186
  4. Clinical Implementation of Diagnostic Genomics

    1. Front Matter
      Pages 187-187
    2. David K. Crockett, Karl V. Voelkerding, Alan F. Brown, Rachel L. Stewart
      Pages 209-234
    3. Hao Ho, Christopher D. Gocke
      Pages 235-244
    4. Michael O. Dorschner
      Pages 245-259
    5. Samya Chakravorty, Arunkanth Ankala, Madhuri R. Hegde
      Pages 261-281
    6. Tina M. Hambuch, Keith Nykamp, Carri-Lyn Rebecca Mead
      Pages 283-306
  5. Genomic Applications in Oncology

    1. Front Matter
      Pages 343-343
    2. Kevin E. Fisher, Linsheng Zhang, Charles E. Hill
      Pages 345-367
    3. Matija Snuderl
      Pages 369-393
    4. Joseph A. Bellairs, Jessica Yesensky, Jamie Ahn Ku, Nishant Agrawal
      Pages 395-414
    5. Thomas J. Giordano
      Pages 415-426
    6. Todd M. Stevens, Justin A. Bishop
      Pages 427-441
    7. Fresia Pareja, Leticia De Mattos-Arruda, Britta Weigelt, Jorge S. Reis-Filho
      Pages 443-461
    8. Reinhard Büttner, Carina Heydt, Sabine Merkelbach-Bruse
      Pages 463-502
    9. Lauren L. Ritterhouse, Wade S. Samowitz
      Pages 503-511
    10. Fátima Carneiro, Ralph H. Hruban
      Pages 513-535
    11. Martin J. Magers, Joshua I. Warrick, Scott A. Tomlins
      Pages 537-567
    12. Sarah Chiang, Luciano G. Martelotto, Britta Weigelt
      Pages 569-602
    13. Martin Köbel, James D. Brenton
      Pages 603-618
    14. Eva Wardelmann, Wolfgang Hartmann
      Pages 619-651
    15. Carlos N. Prieto-Granada, John Van Arnam, Kabeer K. Shah, Aleodor A. Andea, Alexander J. Lazar
      Pages 653-693
  6. Genomic Applications in Inherited and Infectious Diseases, Pharmacogenomics, and the Microbiome

    1. Front Matter
      Pages 695-695
    2. Bryan L. Krock, Rong Mao, Tatiana Tvrdik, D. Hunter Best, Elaine Lyon
      Pages 697-720
    3. Martina I. Lefterova, Carlos J. Suarez, Niaz Banaei, Benjamin A. Pinsky
      Pages 751-766
    4. Mohammad Omar Hussaini, Howard L. McLeod
      Pages 767-782
    5. Wyatt M. Arnold, Elle Simone Hill, Na Fei, Alyson L. Yee, Mariana Salas Garcia, Lauren E. Cralle et al.
      Pages 783-798
  7. Back Matter
    Pages 799-821

About this book


​This book provides the most up-to-date comprehensive discussion of established and emerging genomic technologies and their clinical implementation in molecular diagnostics.  As in its first edition, the book places significant emphasis on implementation roadmaps for various clinical assays including single gene, gene panel, transcriptome sequencing, circulating tumor cells and cell-free DNA sequencing, whole exome, and whole genome assays. Detailed guidance on the central role of the pathologist in the interpretation, reporting, and clinical integration of genomic tests is provided. Expert opinions to help navigate growing compliance, reimbursement, legal and ethical issues are shared in dedicated chapters.

Genomic Applications in Pathology provides a comprehensive resource for practicing molecular pathologists, general and sub-specialized practicing anatomic and clinical pathologists, as well as pathology trainees. The wider target audience continues to include oncologists, geneticists, and other medical and surgical clinicians.


Circulating Tumor Cells Clinical Genomics Genomic Medicine Pharmacogenomics RNAseq Sequencing Assays miRNA Assays

Editors and affiliations

  • George Jabboure Netto
    • 1
  • Karen L. Kaul
    • 2
  1. 1.Professor and Chair of PathologyUniversity of Alabama at BirminghamBirminghamUSA
  2. 2.Department of Pathology and Laboratory Medicine, NorthShore University HealthSystem, Clinical Professor of PathologyUniversity of Chicago Pritzker School of MedicineEvanstonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-96829-2
  • Online ISBN 978-3-319-96830-8
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals