Molecular, Cellular, and Tissue Engineering of the Vascular System

  • Bingmei M. Fu
  • Neil T. Wright

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1097)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Ye Zeng, X. Frank Zhang, Bingmei M. Fu, John M. Tarbell
    Pages 1-27
  3. Ying-Xin Qi, Yue Han, Zong-Lai Jiang
    Pages 69-82
  4. Erica M. C. Kemmerling, Robert A. Peattie
    Pages 157-179
  5. Bingmei M. Fu
    Pages 201-218
  6. L. L. Xiao, W. W. Yan, Y. Liu, S. Chen, B. M. Fu
    Pages 219-234
  7. Bingmei M. Fu
    Pages 235-259
  8. Irsalan Cockerill, Joy-Anne Oliver, Huaxi Xu, Bingmei M. Fu, Donghui Zhu
    Pages 261-278

About this book


This book introduces the latest research in molecular, cellular, and tissue engineering of the vascular system. Topics covered include the roles of endothelial surface glycocalyx as a mechano-sensor and transducer for blood flow, a barrier to water and solute transport across the vascular wall and to the interaction between circulating cells and the vessel wall, the roles of nuclear envelope proteins and nuclear lamina in regulating vascular functions under blood flow-induced forces, and the roles of smooth muscle cells and extracellular components in arterial vasoconstriction. Other topics covered include non-surgical vascular interventions for coronary artery diseases, genesis and mechanisms of atherosclerotic plaque microcalcifications and human abdominal aortic aneurysms, experiments and modelling for red blood cell and tumor cell movement in microcirculation, transport across the blood-brain barrier and its role in Alzheimer’s disease, mathematical models for cell survival after hyperthermia, application of hypothermia in enhancing treatment for brain and spinal cord injuries, and damage of eardrums due to blast waves. This is an ideal book for biomedical engineers and researchers, medical researchers, and students in biomedical engineering and medical sciences.


microvascular transport blood-brain barrier interactions circulation endothelial cells endothelial surface glycocalyx barrier endothelial barrier water transport endothelial surface glycocalyx mechanosensor mechanosensing mechanoregulation extracellular matrix atherosclerotic plaque microcalcifications models thermal regulation cell abdominal aortic aneurysms

Editors and affiliations

  • Bingmei M. Fu
    • 1
  • Neil T. Wright
    • 2
  1. 1.Department of Biomedical EngineeringThe City College of the City University of New YorkNew YorkUSA
  2. 2.Department of Mechanical EngineeringMichigan State UniversityEast LansingUSA

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