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© 2018

Delta Opioid Receptor Pharmacology and Therapeutic Applications

  • Emily M. Jutkiewicz

Benefits

  • Discusses emerging knowledge about the biological function of the delta opioid receptor

  • Describes therapeutic potential of the delta opioid receptor system

  • Describes unique trafficking and signaling properties of the delta opioid receptor

Book

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 247)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Jessica P. Anand, Deanna Montgomery
    Pages 21-51
  3. Ana Vicente-Sanchez, Amynah A. Pradhan
    Pages 73-85
  4. Catherine M. Cahill, Edmund Ong
    Pages 115-127
  5. Richard C. Crist, Toni-Kim Clarke
    Pages 131-145
  6. Khaled Abdallah, Louis Gendron
    Pages 147-177
  7. Isaac J. Dripps, Emily M. Jutkiewicz
    Pages 179-197
  8. Doungkamol Alongkronrusmee, Terrance Chiang, Richard M. van Rijn
    Pages 199-225
  9. L. P. Pellissier, C. N. Pujol, J. A. J. Becker, J. Le Merrer
    Pages 227-260
  10. M. Grant Liska, Marci G. Crowley, Trenton Lippert, Sydney Corey, Cesar V. Borlongan
    Pages 277-299
  11. Louise See Hoe, Hemal H. Patel, Jason N. Peart
    Pages 301-334
  12. Mei Bigliardi-Qi, Paul Bigliardi
    Pages 335-345

About this book

Introduction

This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed.

Keywords

CNS-related diseases Enkephalin biased agonism drug development pain, emotion and addiction receptor trafficking

Editors and affiliations

  • Emily M. Jutkiewicz
    • 1
  1. 1.Department of PharmacologyUniversity of Michigan Medical SchoolAnn ArborUSA

Bibliographic information

  • Book Title Delta Opioid Receptor Pharmacology and Therapeutic Applications
  • Editors Emily M. Jutkiewicz
  • Series Title Handbook of Experimental Pharmacology
  • Series Abbreviated Title Hdb Exp.Pharmacology(formerly:Starke,K.:Eds)
  • DOI https://doi.org/10.1007/978-3-319-95133-1
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2018
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-95131-7
  • Softcover ISBN 978-3-030-06980-3
  • eBook ISBN 978-3-319-95133-1
  • Series ISSN 0171-2004
  • Series E-ISSN 1865-0325
  • Edition Number 1
  • Number of Pages VIII, 348
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Pharmacology/Toxicology
    Neurosciences
    Human Physiology
  • Buy this book on publisher's site
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