Diabetic Nephropathy

Pathophysiology and Clinical Aspects

  • Joris J. Roelofs
  • Liffert Vogt

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Diabetic Nephropathy: Scope of the Problem

    1. Front Matter
      Pages 1-1
    2. Peter Rossing, Marie Frimodt-Møller
      Pages 21-32
    3. Oluwatoyin I. Ameh, Ikechi G. Okpechi, Charles Agyemang, Andre P. Kengne
      Pages 33-44
    4. Esteban Porrini, Maruja Navarro-Díaz, Rosa Rodríguez-Rodríguez, Eduardo Salido
      Pages 65-80
  3. Pathophysiology and Clinical Pathology of the Diabetic Kidney

    1. Front Matter
      Pages 81-81
    2. Liffert Vogt, Joris J. Roelofs
      Pages 83-87
    3. Marcus G. Pezzolesi, Andrzej S. Krolewski
      Pages 89-112
    4. Behzad Najafian, Charles E. Alpers
      Pages 113-140
  4. The Glomerulus

    1. Front Matter
      Pages 141-141
    2. Tri Q. Nguyen, Roel Goldschmeding
      Pages 143-151
    3. Johan van der Vlag, Baranca Buijsers
      Pages 153-170
    4. Gavin I. Welsh, Richard J. Coward
      Pages 171-182
    5. Daphne H. T. IJpelaar
      Pages 183-194
  5. The Tubulointerstitium

    1. Front Matter
      Pages 195-195
    2. Norberto Perico, Ariela Benigni, Giuseppe Remuzzi
      Pages 197-214
    3. Shu Wakino, Kazuhiro Hasegawa, Hiroshi Itoh
      Pages 215-226
    4. Ivonne Loeffler, Gunter Wolf
      Pages 227-251
  6. Microvascular Involvement

    1. Front Matter
      Pages 253-253
    2. Eliane F. E. Wenstedt, Liffert Vogt
      Pages 255-276
    3. Marco van Londen, Niek Hessels, Annebelle Michielsen, Nicolien Kasper, Gerjan Navis
      Pages 293-304
    4. Esmeralda K. Bosma, Cornelis J. F. van Noorden, Ingeborg Klaassen, Reinier O. Schlingemann
      Pages 305-321
  7. Macrovascular Involvement

    1. Front Matter
      Pages 323-323
    2. Gema Ruiz-Hurtado, Luis M. Ruilope
      Pages 325-335
    3. Bert-Jan van den Born, Fouad Amraoui
      Pages 337-355
    4. Raphael Duivenvoorden
      Pages 357-372
  8. Experimental Designs

    1. Front Matter
      Pages 373-373
    2. Isabel Nguyen, Arianne van Koppen, Jaap A. Joles
      Pages 375-413
    3. Marjolein Y. A. M. Kroonen, Hiddo J. L. Heerspink, Dick de Zeeuw
      Pages 415-431
  9. Therapy of Diabetic Nephropathy

    1. Front Matter
      Pages 433-433
    2. Gerald Vervoort
      Pages 435-450
    3. Jesper Kers, Frederike J. Bemelman
      Pages 451-467
  10. Future Developments

    1. Front Matter
      Pages 469-469
    2. Maria Pallayova, Gopesh K. Modi, Indranil Dasgupta
      Pages 471-486
    3. Massimo Papale, Francesca Conserva, Paola Pontrelli, Loreto Gesualdo
      Pages 487-513
    4. Nienke M. A. Idzerda, Michelle J. Pena, Dick de Zeeuw, Hiddo J. L. Heerspink
      Pages 515-539
  11. Back Matter
    Pages 541-548

About this book


This book provides an overview of the most up-to-date research on diabetic nephropathy and the current understanding of its pathogenesis, clinical features and socio-economic developments. Written by leading experts in the field, it provides a comprehensive synthesis of clinical and pathophysiological aspects from a mechanism-based point of view, and reviews evidence-based treatment modalities for the prevention and management of diabetic nephropathy. In addition, closely related areas such as diabesity, diabetic eye disease and macrovascular involvement in diabetes are addressed.

Diabetic Nephropathy will be of interest for nephrologists, diabetologists, internists, transplant physicians, public health professionals, basic scientists, geneticists, epidemiologists, pathologists, and molecular and cell biologists working in the field of diabetes and its complications.


Chronic Kidney Disease Type 2 Diabetes Clinical Aspects Basic Research Research and Clinical Science

Editors and affiliations

  • Joris J. Roelofs
    • 1
  • Liffert Vogt
    • 2
  1. 1.Department of PathologyAmsterdam University Medical Centers, University of AmsterdamAmsterdamThe Netherlands
  2. 2.Department of Internal MedicineAmsterdam University Medical Centers, University of AmsterdamAmsterdamThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-93520-1
  • Online ISBN 978-3-319-93521-8
  • Buy this book on publisher's site
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