Introduction to Evolutionary Genomics

  • Naruya Saitou

Part of the Computational Biology book series (COBO, volume 17)

Table of contents

  1. Front Matter
    Pages i-xxv
  2. Basic Processes of Genome Evolution

    1. Front Matter
      Pages 1-1
    2. Naruya Saitou
      Pages 23-36
    3. Naruya Saitou
      Pages 37-67
    4. Naruya Saitou
      Pages 69-108
    5. Naruya Saitou
      Pages 109-148
    6. Naruya Saitou
      Pages 149-180
  3. Evolving Genomes

    1. Front Matter
      Pages 181-181
    2. Naruya Saitou
      Pages 183-199
    3. Naruya Saitou
      Pages 201-220
    4. Naruya Saitou
      Pages 221-240
    5. Naruya Saitou
      Pages 241-245
    6. Naruya Saitou
      Pages 247-272
    7. Naruya Saitou
      Pages 273-289
  4. Methods for Evolutionary Genomics

    1. Front Matter
      Pages 291-291
    2. Naruya Saitou
      Pages 293-306
    3. Naruya Saitou
      Pages 307-323
    4. Naruya Saitou
      Pages 325-360
    5. Naruya Saitou
      Pages 361-393
    6. Naruya Saitou
      Pages 395-466
    7. Naruya Saitou
      Pages 467-496
  5. Back Matter
    Pages 497-504

About this book


This authoritative textbook/reference presents a comprehensive introduction to the field of evolutionary genomics. The opening chapters describe the fundamental concepts in molecular biology and genome evolution for readers without any prior background in this area. This is followed by a detailed examination of genome evolution in various different groups of organisms. The text then concludes with a review of practical methods essential to researchers in the field.

This updated and revised new edition also features historical perspectives on contributions to evolutionary genomics from related fields such as molecular evolution, genetics, and numerical taxonomy.

Topics and features:

  • Introduces the basics of molecular biology, covering protein structure and diversity, as well as DNA replication, transcription, and translation
  • Examines the phylogenetic relationships of DNA sequences, and the processes of mutation, neutral evolution, and natural selection
  • Presents a brief evolutionary history of life, surveying the key features of the genomes of prokaryotes, eukaryotes, viruses and phages, vertebrates, and humans
  • Reviews the various biological “omic” databases, and discusses the analysis of homologous nucleotide and amino acid sequences
  • Provides an overview of the experimental sequencing of genomes and transcriptomes, and the construction of phylogenetic trees
  • Describes methods for estimating of evolutionary distances, and performing studies of population genetics
  • Supplies additional supporting material at an associated website

Serving as an indispensable textbook for graduate and advanced undergraduate courses on evolutionary genomics, this accessible overview will also prove invaluable to researchers from both computer science and the biological sciences seeking a primer on the field.

Dr. Naruya Saitou is a Professor in the Division of Population Genetics at the National Institute of Genetics, and a Professor in the Department of Genetics at the Graduate University for Advanced Studies, Mishima, Japan. He is also a Professor in the Department of Biological Sciences at the University of Tokyo, Japan.


Bioinformatics Evolutionary Genomics Genomics Molecular Evolution Phylogeny

Authors and affiliations

  • Naruya Saitou
    • 1
  1. 1.Division of Population GeneticsNational Institute of Genetics (NIG)MishimaJapan

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