© 2018

Orthopedic Biomaterials

Progress in Biology, Manufacturing, and Industry Perspectives

  • Bingyun Li
  • Thomas Webster


  • Provides an industry perspective on technologies related to orthopedic biomaterials

  • Thoroughly details the modulation of innate inflammatory reactions in the application of orthopedic biomaterials

  • Details state-of-the-art research on additive manufacturing of orthopedic implants


Table of contents

  1. Front Matter
    Pages i-viii
  2. Design, Manufacturing, Assessment, and Applications

    1. Front Matter
      Pages 1-1
    2. Maryam Tilton, Gregory S. Lewis, Guha P. Manogharan
      Pages 21-55
    3. Wenjun Zheng, Qilin Wei, Xiaojie Xun, Ming Su
      Pages 57-66
    4. Krishanu Ghosal, Rohit Khanna, Kishor Sarkar
      Pages 67-88
    5. Stefan Balko, Joanna F. Weber, Stephen D. Waldman
      Pages 123-147
  3. Biology and Clinical and Industrial Perspectives

    1. Front Matter
      Pages 173-173
    2. Lindsey N. Bravin, Matthew J. Dietz
      Pages 175-198
    3. Tzuhua Lin, Eemeli Jämsen, Laura Lu, Karthik Nathan, Jukka Pajarinen, Stuart B. Goodman
      Pages 199-218
    4. Dukens LaBaze, Hongshuai Li
      Pages 243-286
    5. Balaji Prabhu, Andreas Karau, Andrew Wood, Mahrokh Dadsetan, Harald Liedtke, Todd DeWitt
      Pages 287-344
    6. Robert S. Liddell, John E. Davies
      Pages 381-400
    7. Scott M. Tucker, J. Spence Reid, Gregory S. Lewis
      Pages 401-428

About this book


This book covers the latest progress in the biology and manufacturing of orthopedic biomaterials, as well as key industry perspectives. Topics covered include the development of biomaterial-based medical products for orthopedic applications, anti-infection technologies for orthopedic implants, additive manufacturing of orthopedic implants, and more. This is an ideal book for graduate students, researchers and professionals working with orthopedic biomaterials and tissue engineering.

This book also:

Provides an industry perspective on technologies to prevent orthopedic implant related infection

Thoroughly covers how to modulate innate inflammatory reactions in the application of orthopedic biomaterials

Details the state-of-the-art research on 3D printed porous bone constructs


3D orthopedic tissue engineering 3D printing for Orthopaedics Absorbable orthopaedic biomaterials Absorbable orthopaedic biomaterials polymers Additive Manufacturing Orthopaedic Implants Antimicrobial peptides Bioceramic bioglass bone scaffolds Biodegradable metals implants Biomaterials Total Joint Arthroplasty Calcium phosphates Immunomodulation bone tissue engineering Materials orthopaedic applications Mechanical Cartilage Tissue Engineering Orthopaedic biomaterials technologies Orthopaedic Nanomaterials Orthopedic biomaterials tissue engineering

Editors and affiliations

  • Bingyun Li
    • 1
  • Thomas Webster
    • 2
  1. 1.Department of Orthopedics School of MedicineWest Virginia UniversityMorgantownUSA
  2. 2.Department of Chemical EngineeringNortheastern UniversityBostonUSA

About the editors

Bingyun Li is a full Professor with tenure at School of Medicine West Virginia University. He is a member of the Society for Biomaterials (SFB), Orthopedic Research Society (ORS), American Society for Microbiology (ASM), Materials Research Society (MRS), American Chemical Society (ACS), International Chinese Musculoskeletal Research Society (ICMRS), and Chinese Association for Biomaterials (CAB). Professor Li has served as topic chair of Infection and Inflammation of the ORS Program Committee, vice-chair and chair of Orthopedic Biomaterials Special Interest Group of SFB, Chief Editor of ICMRS Newsletter, and inaugural treasurer of CAB. Professor Li’s research focuses on advanced materials, nanomedicine, infection, immunology, and drug delivery. He has supervised 84 trainees, and his lab group has published more than 76 peer-reviewed articles, nine book chapters, 12 provisional/full patents, and 122 abstracts. Professor Li has given 48 invited talks and has received multiple prestigious awards including the Berton Rahn Prize from AO Foundation, the Pfizer Best Scientific Paper Award from Asia Pacific Orthopedic Association, and the Collaborative Exchange Award from Orthopedic Research Society.

Thomas Webster is the Chemical Engineering Department Chair and Art Zafiropoulo Endowed Chair at Northeastern University. Prof. Webster has graduated 144 students. His lab group published 9 textbooks, 48 book chapters, 403 articles, and 32 provisional/full patents. Prof. Webster has received numerous honors: 2012, Fellow, American Institute for Medical and Biological Engineering; 2013, Fellow, Biomedical Engineering Society; 2015, Wenzhou 580 Award; 2015, Zheijang 1000 Talent Program; 2016, IMRC Chinese Academy of Science Lee-Hsun Lecture Award; 2016, Fellow, Biomaterials Science and Engineering; and 2016, Acta Biomaterialia Silver Award. He also frequently appears on the BBC, NBC, ABC, Fox, National Geographic, Discovery Channel and many other news outlets talking about science. Prof. Webster was also recently inducted as a Fellow into the National Academy of Inventors based on the formation of 11 companies with 4 FDA approved products in orthopedics. Prof. Webster was also recently inducted as a Fellow into the National Academy of Inventors based on the formation of 11 companies with 4 FDA approved products in orthopedics.

Bibliographic information

Industry Sectors
Surgery & Anesthesiology
Consumer Packaged Goods