© 2018

The Microbiome in Rheumatic Diseases and Infection

  • Gaafar Ragab
  • T. Prescott Atkinson
  • Matthew L. Stoll


  • Offers practicing clinicians intimate knowledge of the microbiome’s role in rheumatic diseases and how this influences their daily practice

  • Includes detailed basic science and immunology sections for clinicians to better understand the function of the microbiome

  • Covers the role of infectious organisms in major rheumatic diseases including rheumatoid arthritis and vasculitis

  • Experts from around the world offer a comprehensive and international perspective on the topic


Table of contents

  1. Front Matter
    Pages i-xxii
  2. Introductory Chapters

    1. Front Matter
      Pages 1-1
    2. Matthew L. Stoll
      Pages 3-11
    3. Philipp Rausch, Axel Künstner
      Pages 29-42
  3. Immunogenetics of the Host Response to Infection

    1. Front Matter
      Pages 43-43
    2. T. Prescott Atkinson
      Pages 45-54
    3. Daniel M. Altmann, Catherine J. Reynolds, Rosemary J. Boyton
      Pages 55-62
    4. David R. Webb
      Pages 63-72
  4. Infectious Agents

    1. Front Matter
      Pages 73-73
    2. Maria Kaparakis-Liaskos, Mario M. D’Elios
      Pages 87-96
    3. Guliz Erdem, Edward L. Kaplan
      Pages 97-102
    4. T. Prescott Atkinson
      Pages 103-111
    5. Lazaros I. Sakkas, Dimitrios P. Bogdanos
      Pages 113-127
    6. Massimo Galli, Giorgio Bozzi, Andrea Giacomelli
      Pages 129-138
    7. Ester Roffe, Philip M. Murphy
      Pages 139-147
  5. The Role of Infectious Agents in Rheumatic Diseases

    1. Front Matter
      Pages 149-149
    2. Esraa M. Eloseily, Randy Q. Cron
      Pages 151-182
    3. Matthew L. Stoll, S. Louis Bridges Jr., Maria I. Danila
      Pages 183-199

About this book


This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms in autoimmunity and the deeply related rheumatic diseases. This book comprehensively explains the emerging microbiome research through the interrelationships of biomedical sciences, including: immunology, microbiology, bioinformatics, and, with special emphasis, the clinical aspect of rheumatology. It examines the interplay between infectious organisms and major autoimmune diseases, including rheumatoid arthritis, psoriatic arthritis, juvenile arthritis, systemic lupus erythematosus, and vasculitis, and explains how to apply that knowledge to diagnostic techniques and treatment decisions. The international team of expert authors provides insight into current therapies and future interventions specifically targeting the microbiota and explores the impact of our deeper understanding on enhancing personalized medicine. The Microbiome in Rheumatic Diseases and Infection is an essential resource for rheumatologists, pediatricians, internists, microbiologists, and critical care providers caring for children and adults with rheumatic diseases.


microbiome immunogenetics bacterial disease rheumatic disease infection autoimmunity viral disease protozoal infections

Editors and affiliations

  • Gaafar Ragab
    • 1
  • T. Prescott Atkinson
    • 2
  • Matthew L. Stoll
    • 3
  1. 1.Faculty of MedicineCairo UniversityCairoEgypt
  2. 2.University of AlabamaBirminghamUSA
  3. 3.University of AlabamaBirminghamUSA

About the editors

Gaafar Ragab, MD is Professor of Internal Medicine at Cairo University and Fellow of the American College of Rheumatology. He was previously Head of the Clinical Immunology and Rheumatology unit at Cairo University.

T. Prescott Atkinson, MD, PhD is Professor/ Director of the Division of Pediatric Allergy, Asthma & Immunology at The Children’s Hospital of Alabama.

Matthew L. Stoll, MD, PhD is Associate Professor in the Division of Pediatric Rheumatology at the University of Alabama at Birmingham.

Bibliographic information

  • Book Title The Microbiome in Rheumatic Diseases and Infection
  • Editors Gaafar Ragab
    T. Prescott Atkinson
    Matthew L. Stoll
  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-79025-1
  • Softcover ISBN 978-3-030-07708-2
  • eBook ISBN 978-3-319-79026-8
  • Edition Number 1
  • Number of Pages XXII, 490
  • Number of Illustrations 5 b/w illustrations, 34 illustrations in colour
  • Topics Rheumatology
    Infectious Diseases
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology