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© 2018

Stromal Immunology

  • Benjamin M.J Owens
  • Matthew A. Lakins
  • Discusses the newfound role of stromal cells in immune response

  • Provides a solid grounding in the fundamentals of stromal immunology

  • First comprehensive resource about stromal immunology

Book

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1060)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Joshua D’Rozario, David Roberts, Muath Suliman, Konstantin Knoblich, Anne Fletcher
    Pages 1-22
  3. Paul M. Kaye
    Pages 23-36
  4. Jason D. Turner, Amy J. Naylor, Christopher Buckley, Andrew Filer, Paul-Peter Tak
    Pages 37-54
  5. C. G. Mueller, S. Nayar, J. Campos, F. Barone
    Pages 55-72
  6. Hafsa Munir, Lewis S. C. Ward, Helen M. McGettrick
    Pages 73-98
  7. Alice E. Denton, Edward W. Roberts, Douglas T. Fearon
    Pages 99-114
  8. Iryna V. Pinchuk, Don W. Powell
    Pages 115-129
  9. Back Matter
    Pages 147-151

About this book

Introduction

Research into and interest in the role of stromal cells in immunology has exploded over the past 15 years. The conventional view that placed non-hematopoietic stromal cells as passive, structural, and supportive entities has now been replaced with an appreciation that these cells have active, dynamic roles during immune responses, and thus impact on the pathophysiology of multiple immune-mediated diseases. This book serves to provide solid grounding in the fundamentals of stromal immunology, focusing on the biological aspects of their function in addition to highlighting key areas for the development of the field in the future. The book is also a unique source of information on emerging concepts that place stromal cells from outside lymphoid organs as major contributors to the biology of diverse conditions, such as rheumatoid arthritis, chronic parasitic infection, inflammatory bowel disease, and cancer.

Keywords

Cell Biology Immunotherapy Inflammation Stroma Stromal Cells immunology

Editors and affiliations

  • Benjamin M.J Owens
    • 1
  • Matthew A. Lakins
    • 2
  1. 1.Somerville CollegeUniversity of OxfordOxfordUK
  2. 2.F-star Biotechnology Ltd.CambridgeUK

About the editors

Dr. Benjamin Owens is Head of Business Development at EUSA Pharma and an RF Lecturer in Medicine at Somerville College, University of Oxford. His prior academic research programmes focused on the role of intestinal stromal cells in human chronic intestinal inflammation. In addition to his role in Industry, he teaches stromal immunology to final year medical students.

Dr. Matthew Lakins is a Senior Scientist at F-star Biotechnology Ltd. in Cambridge, UK. Prior to this he was an MRC Career Development Fellow at the MRC Cancer Unit at the University of Cambridge. Here his research interests lay at the interface of tumor-associated stromal biology and immunology, ultimately working toward understanding and exploiting the ability of the tumor microenvironment to manipulate host tumor immunogenicity.

Together, Dr. Owens and Dr. Lakins founded the BSI Stromal Immunology affinity group in 2010 and have since organized two international meetings in York  and Cambridge.

Bibliographic information

  • Book Title Stromal Immunology
  • Editors Benjamin M.J Owens
    Matthew A. Lakins
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Adv Exp Med Biol
  • DOI https://doi.org/10.1007/978-3-319-78127-3
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2018
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-78125-9
  • Softcover ISBN 978-3-030-08621-3
  • eBook ISBN 978-3-319-78127-3
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages XIII, 151
  • Number of Illustrations 0 b/w illustrations, 15 illustrations in colour
  • Topics Immunology
    Cell Biology
  • Buy this book on publisher's site
Industry Sectors
Biomedicine
Biotechnology
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