© 2018

Channelopathies in Heart Disease

  • Dierk Thomas
  • Carol Ann Remme

Part of the Cardiac and Vascular Biology book series (Abbreviated title: Card. vasc. biol., volume 6)

Table of contents

  1. Front Matter
    Pages i-vi
  2. Carol Ann Remme, Dierk Thomas
    Pages 1-5
  3. (Dys)Function of Cardiac Ion Channels

    1. Front Matter
      Pages 7-7
    2. Morten B. Thomsen
      Pages 47-75
    3. Jordi Heijman, Cristina E. Molina, Niels Voigt
      Pages 77-96
    4. Annalisa Bucchi, Chiara Piantoni, Andrea Barbuti, Dario DiFrancesco, Mirko Baruscotti
      Pages 97-126
    5. Claire Hopton, Luigi Venetucci, Miriam Lettieri
      Pages 127-144
  4. Cardiac Channelopathies: Clinical and Genetic Findings

    1. Front Matter
      Pages 145-145
    2. Lia Crotti, Maria-Christina Kotta, Silvia Castelletti
      Pages 147-185
    3. Apichai Khongphatthanayothin, Koonlawee Nademanee
      Pages 187-214
    4. Patrick A. Schweizer
      Pages 215-229
    5. Riccardo Maragna, Carlo Napolitano
      Pages 231-256
    6. Ann-Kathrin Rahm, Hugo A. Katus, Dierk Thomas
      Pages 277-322
    7. Florence Kyndt, Jean-Baptiste Gourraud, Julien Barc
      Pages 323-358
  5. Research into Cardiac Channelopathies: New Avenues

    1. Front Matter
      Pages 359-359
    2. Esperanza Agullo-Pascual, Alejandra Leo-Macias, Donna R. Whelan, Mario Delmar, Eli Rothenberg
      Pages 361-378

About this book


This book provides an expert overview on ion channel-related arrhythmia mechanisms, and describes important advances in our understanding of how ion channel dysfunction causes cardiac disease. Both, scientific findings and clinical implications are presented and discussed by scientists who have considerably contributed to the field.

The book is organized in three parts: part I  treats the molecular and electrophysiological mechanisms of function and dysfunction of ion channels,  part II focuses on genetics and clinical findings, whereas part III describes novel research techniques, the use of stem cells and animal models and provides an outlook on future investigations and applications.

The book is written for scientists in Cardiovascular Biology and Neuroscience and will be of general interest to Medical Doctors in Cardiology, Cardiac Electrophysiology and related disciplines.



Ion channels Channelopathies Electrophysiology Cardiac arrhythmias Cardiac disease Computational modeling induced pluripotent stem cells iPSC Cardiomyocytes Animal models Heart

Editors and affiliations

  • Dierk Thomas
    • 1
  • Carol Ann Remme
    • 2
  1. 1.Department of Cardiology and HCR (Heidelberg Center for Heart Rhythm Disorders)University Hospital HeidelbergHeidelbergGermany
  2. 2.Dept. of Clinical & Experimental CardiologyAcademic Medical Center, University of AmsterdamAmsterdamThe Netherlands

About the editors

Prof. Dr. med. Dierk Thomas is Associate Professor at the University of Heidelberg and Head of the Cardiac Electrophysiology Department, Medical University Hospital, University of Heidelberg, Germany.

Dr. Carol Ann Remme is Associate Professor and Principal Investigator at the Department of Clinical and Experimental Cardiology, Academic Medical Center, Amsterdam, The Netherlands.

Bibliographic information

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