Activation of Viruses by Host Proteases

  • Eva Böttcher-Friebertshäuser
  • Wolfgang Garten
  • Hans Dieter Klenk

Table of contents

  1. Front Matter
    Pages i-x
  2. Viral Proteins Activated By Host Proteases

    1. Front Matter
      Pages 1-1
    2. Summer E. Galloway, Bo Liang, David A. Steinhauer
      Pages 3-26
    3. Everett Clinton Smith, Rebecca Ellis Dutch
      Pages 27-45
    4. Antonella Pasquato, Laura Cendron, Stefan Kunz
      Pages 47-70
    5. Markus Hoffmann, Heike Hofmann-Winkler, Stefan Pöhlmann
      Pages 71-98
    6. Viktor Volchkov, Hans Dieter Klenk
      Pages 99-108
    7. Franz X. Heinz, Karin Stiasny
      Pages 109-132
  3. Activating Proteases

  4. Protease Inhibitors

    1. Front Matter
      Pages 277-277
    2. Torsten Steinmetzer, Kornelia Hardes
      Pages 279-325
  5. Back Matter
    Pages 327-335

About this book


This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy.

This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.


proteolytic activation pathogenesis spread of infection substrate specificity compartimentalization antiviral therapy

Editors and affiliations

  • Eva Böttcher-Friebertshäuser
    • 1
  • Wolfgang Garten
    • 2
  • Hans Dieter Klenk
    • 3
  1. 1.Institut für VirologiePhilipps UniversitätMarburgGermany
  2. 2.Institut für VirologiePhilipps UniversitätMarburgGermany
  3. 3.Institut für VirologiePhilipps-UniversitätMarburgGermany

Bibliographic information

Industry Sectors
Health & Hospitals