Theoretical and Applied Aspects of Systems Biology

  • Fabricio Alves Barbosa da Silva
  • Nicolas Carels
  • Floriano Paes Silva Junior

Part of the Computational Biology book series (COBO, volume 27)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Fundamentals

    1. Front Matter
      Pages 1-1
    2. Rafael V. Carvalho, Fons J. Verbeek, Clarimar J. Coelho
      Pages 3-26
    3. Marcelo Trindade dos Santos, Ana Paula Barbosa do Nascimento, Fernando Medeiros Filho, Fabricio Alves Barbosa da Silva
      Pages 27-39
    4. Domenico Sgariglia, Alessandra Jordano Conforte, Luis Alfredo Vidal de Carvalho, Nicolas Carels, Fabricio Alves Barbosa da Silva
      Pages 41-55
    5. Marcio Argollo de Menezes
      Pages 57-69
    6. Stephen Woloszynek, Zhengqiao Zhao, Gregory Ditzler, Jacob R. Price, Erin R. Reichenberger, Yemin Lan et al.
      Pages 71-112
    7. Alexandre Galvão Patriota, Maciel Calebe Vidal, Davi Augusto Caetano de Jesus, André Fujita
      Pages 113-125
  3. Applied Systems Biology

    1. Front Matter
      Pages 127-127
    2. Edward Rietman, Jack A. Tuszynski
      Pages 139-157
    3. Melissa Lever, Thiago C. Hirata, Pedro S. T. Russo, Helder I. Nakaya
      Pages 159-173
    4. Alessandra Jordano Conforte, Milena Magalhães, Tatiana Martins Tilli, Fabricio Alves Barbosa da Silva, Nicolas Carels
      Pages 175-194
    5. Fabricio Alves Barbosa da Silva, Fernando Medeiros Filho, Thiago Castanheira Merigueti, Thiago Giannini, Rafaela Brum, Laura Machado de Faria et al.
      Pages 195-220
    6. Larissa Catharina, Marcio Argollo de Menezes, Nicolas Carels
      Pages 221-242
    7. Celia Martins Cortez, Maria Clicia Stelling de Castro, Vanessa de Freitas Rodrigues, Camila Andrade Kalil, Dilson Silva
      Pages 243-259

About this book


Systems Biology is a rapidly expanding field and comprises the study of biological systems through mathematical modeling and the analysis of large volumes of biological data. This book presents the theoretical foundations of Systems Biology, as well as its application in studies on human hosts, pathogens and associated diseases.  This book presents several chapters written by renowned experts in the field. Some topics discussed in depth in this book include: computational modeling of multidrug-resistant bacteria, systems biology of cancer, systems immunology, cellular reprogramming, bio-modeling using Petri nets, computational modeling of neuronal circuits, reconstruction and analysis of gene regulatory networks.


Systems Biology Precision Medicine Modeling and simulation of biological systems Systems Biology of cancer Networks in Systems Biology

Editors and affiliations

  • Fabricio Alves Barbosa da Silva
    • 1
  • Nicolas Carels
    • 2
  • Floriano Paes Silva Junior
    • 3
  1. 1.Graduate Program in Computational BiologyOswaldo Cruz FoundationRio de JaneiroBrazil
  2. 2.Graduate Program in Computational BiologyOswaldo Cruz FoundationRio de JaneiroBrazil
  3. 3.Graduate Program in Computational BiologyOswaldo Cruz FoundationRio de JaneiroBrazil

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