© 2018

Engineering and Application of Pluripotent Stem Cells

  • Ulrich Martin
  • Robert Zweigerdt
  • Ina Gruh
  • Presents different bioengineering strategies applied to pluripotent stem cells

  • Explores the (re)programming to pluripotency

  • Reviews the use of pluripotent stem cells for tissue engineering and drug screening


Part of the Advances in Biochemical Engineering/Biotechnology book series (ABE, volume 163)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Neta Lavon, Michal Zimerman, Joseph Itskovitz-Eldor
    Pages 23-37
  3. Frauke Hausburg, Julia Jeannine Jung, Robert David
    Pages 71-115
  4. Xin Yi Chan, Morgan B. Elliott, Bria Macklin, Sharon Gerecht
    Pages 147-168
  5. O. Kyriakides, J. A. Halliwell, P. W. Andrews
    Pages 187-206
  6. Klaus Christensen, Filip Roudnicky, Christoph Patsch, Mark Burcin
    Pages 207-220
  7. Back Matter
    Pages 221-228

About this book


​This book reviews the latest biotechnological advances with pluripotent stem cells, exploring their application in tissue engineering and medicinal chemistry. Chapters from expert contributors cover topics such as the production of transgene-free induced pluripotent stem cells (iPSCs), expansion, controlled differentiation and programming of pluripotent stem cells, and their genetic instability. Particular attention is given to the application of the pluripotent stem cells for vascularision of engineered tissue and for drug screening.

This book will appeal to researchers working in regenerative medicine and drug discovery, and to bioengineers and professionals interested in stem cell research.


pluripotency small molecules Transgene-Free iPSCs Genome engineering drug screening tissue engineering Pluripotent stem cells differentiation matrix composition

Editors and affiliations

  • Ulrich Martin
    • 1
  • Robert Zweigerdt
    • 2
  • Ina Gruh
    • 3
  1. 1.Leibniz Research Labs for BiotechnologyHannover Medical School (MHH)HannoverGermany
  2. 2.Leibniz Research Labs for BiotechnologyHannover Medical School (MHH)HannoverGermany
  3. 3.Leibniz Research Labs for BiotechnologyHannover Medical School (MHH)HannoverGermany

Bibliographic information

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