Table of contents

  1. Front Matter
    Pages i-x
  2. Zihong He, Tuomo Rankinen, Arthur S. Leon, James S. Skinner, André Tchernof, Claude Bouchard
    Pages 25-42 Open Access
  3. Rasmus J. O. Sjögren, Magnus H. L. Lindgren Niss, Anna Krook
    Pages 67-81 Open Access
  4. Paula Valente-Silva, Jorge Lira Ruas
    Pages 83-91 Open Access
  5. Mohammad Rashedul Islam, Michael F. Young, Christiane D. Wrann
    Pages 93-102 Open Access

About this book


The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.


metabolic diseases obesity type 2 diabetes muscle glycogen skeletal muscle microRNAs Tryptophan-kynurenine metabolites FNDC5/irisin AMPK human brown adipose tissue plasticity Open Access

Editors and affiliations

  • Bruce Spiegelman
    • 1
  1. 1.Dana-Farber Cancer InstituteHarvard Medical SchoolBostonUSA

About the editors

Bruce Spiegelman is a Professor of Cancer Biology at Harvard Medical School and a Stanley J. Korsmeyer Professor of Cell Biology and Medicine

Bibliographic information

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