© 2019

Age of Onset of Mental Disorders

Etiopathogenetic and Treatment Implications

  • Giovanni de Girolamo
  • Patrick D. McGorry
  • Norman Sartorius

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Giovanni Fiorito, Carlotta Sacerdote, Paolo Vineis
    Pages 15-28
  3. Jouko Miettunen, Johanna Immonen, John J. McGrath, Matti Isohanni, Erika Jääskeläinen
    Pages 55-73
  4. Jessica Dagani, Ross J. Baldessarini, Giulia Signorini, Olav Nielssen, Giovanni de Girolamo, Matthew Large
    Pages 75-110
  5. Nefize Yalin, Allan H. Young
    Pages 111-124
  6. Jeroen S. Legerstee, Bram Dierckx, Elisabeth M. W. J. Utens, Frank C. Verhulst, Carola Zieldorff, Gwen C. Dieleman et al.
    Pages 125-147
  7. Adrian B. Kelly, Megan Weier, Wayne D. Hall
    Pages 149-167
  8. Jason P. Connor, Megan Weier, Wayne D. Hall
    Pages 169-182
  9. Andrew M. Chanen, Katherine N. Thompson
    Pages 183-201
  10. Angela Favaro, Paolo Busetto, Enrico Collantoni, Paolo Santonastaso
    Pages 203-216
  11. David Coghill, Phillip Asherson, Stephen V. Faraone, Luis A. Rohde
    Pages 217-236
  12. Sandra Landwehr, Ralph Brinks, Annika Hoyer
    Pages 237-253

About this book


This book presents a thorough and critical review of current  knowledge about  the age of onset of mental disorders. The opening chapters offer information about the impact of the age of onset on the clinical picture, course, and outcome of physical illnesses, and about  the neurobiological implications and correlates of different ages of onset. The impact and correlates of the ages of onset of all the most important mental disorders are then discussed in detail by internationally renowned scientists. The background to the book is the recognition that a better understanding of age of onset makes it possible to estimate the lifetime risk of disorders, helps to elucidate pathogenesis, and facilitates efficient, targeted clinical management. The book will be of value for clinicians, mental health professionals, mental health researchers, epidemiologists, and different stakeholders in the mental health field.


Diagnosis and prognosis of mental illness mental disorders in childhood schizophrenia bipolar illness course of mental illness classification of mental disorders mental health service development outcome of mental disorders developmental psychopathology

Editors and affiliations

  • Giovanni de Girolamo
    • 1
  • Patrick D. McGorry
    • 2
  • Norman Sartorius
    • 3
  1. 1.Unit of Psychiatric Epidemiology and EvaluationIRCCS St John of God Clinical Research CenterBresciaItaly
  2. 2.Orygen The National Centre of ExcellenceUniversity of MelbourneVictoriaAustralia
  3. 3.Association for the Improvement of Mental Health ProgrammesGenevaSwitzerland

About the editors

Giovanni de Girolamo, M.D., leads the Psychiatric Epidemiology and Evaluation Unit at the IRCCS St. John of God Clinical Research Centre, Brescia (Italy), and is a Professor at the Faculty of Psychology at the Catholic University of the Sacred Heart, Milan (Italy). From 1988 to 1994 he was an Associate Professional Officer at the Division of Mental Health, World Health Organization, Geneva; after his return to Italy, he has worked at the Italian N.I.H. in Rome and at the Department of Mental Health in Bologna. He has been a principal investigator for a range of studies covering  a variety of mental health areas, and has been the PI of the Italian site participating to the World Mental Health Survey Initiative. He is currently the principal investigator for the Italian site of the European projects “THE MILESTONE PROJECT: Managing the Link and Strengthening Transition from Child to Adult Mental Health Care” and RADAR-CNS. Prof. de Girolamo has published more than 250 papers and authored or co-authored several books and book chapters. 

Norman Sartorius was the Director of the Division of Mental Health at the World Health Organization (WHO) and subsequently President of the World Psychiatric Association (WPA) and then  President of the Association of European Psychiatrists). He is currently President of the Association for the Improvement of Mental Health Programmes and a member of the Geneva Prize Foundation, having previously been its President. Professor Sartorius was professor of psychiatry at the University of Geneva and now holds professorial appointments at the Universities of London and Zagreb and at several other universities in the USA and China. He has published more than 400 articles in scientific journals, authored or co-authored a number of books and edited many others. He is an honorary fellow of the Royal College of Psychiatrists of the United Kingdom, of the American College of Psychiatry, of the Royal Australian and New Zealand College of Psychiatrists and of numerous other professional associations. He is also a Distinguished Fellow of the American Psychiatric Association and honorary member of medical academies in Peru, Mexico and Croatia and holds honorary doctorates from universities in the Cheech Republic, Denmark, Romania, Sweden and the UK. He is also a chief editor of  Current Opinion in Psychiatry and a member of the editorial boards of a number of scientific journals.  

Patrick McGorry is a Professor of Youth Mental Health at the University of Melbourne, and Executive Director of Orygen, the National Centre of Excellence in Youth Mental Health. He is also President of the Society for Mental Health Research in Australia, President of the Schizophrenia International Research Society, and a founding member and Treasurer of the International Early Psychosis Association (IEPA). Leading researcher and innovator in early intervention for emerging mental illness in young people , Prof. McGorry has authored or co-authored over 300 peer-reviewed articles, more than 50 book chapters and 6 books. He currently serves as Editor in Chief of the journal Early Intervention in Psychiatry, and on the Editorial Board of Schizophrenia Research.


Bibliographic information

  • Book Title Age of Onset of Mental Disorders
  • Book Subtitle Etiopathogenetic and Treatment Implications
  • Editors Giovanni de Girolamo
    Patrick D. McGorry
    Norman Sartorius
  • DOI
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-72618-2
  • eBook ISBN 978-3-319-72619-9
  • Edition Number 1
  • Number of Pages XVI, 261
  • Number of Illustrations 6 b/w illustrations, 24 illustrations in colour
  • Topics Psychiatry
    Public Health
    Human Genetics
    Medical Education
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals