Intracytoplasmic Sperm Injection

Indications, Techniques and Applications

  • Gianpiero D. Palermo
  • E. Scott Sills

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Douglas T. Carrell, Timothy G. Jenkins, Benjamin R. Emery, James M. Hotaling, Kenneth I. Aston
    Pages 23-38
  3. Océane Albert, Bernard Robaire
    Pages 85-98
  4. Seyed Abolghasem Mirroshandel, Fatemeh Ghasemian
    Pages 99-122
  5. Omer A. Raheem, Tung-Chin Hsieh
    Pages 123-141
  6. Daniel Luna Origgi, Javier García-Ferreyra
    Pages 143-155
  7. Toru Suzuki, Anthony C. F. Perry
    Pages 169-181
  8. Back Matter
    Pages 193-198

About this book


This unique, comprehensive text on the male factor infertility experience centers on the current background, applications and techniques for intracytoplasmic sperm injection (ICSI), one of the more commonly utilized procedures in modern assisted reproduction for male infertility, offering insights into the rationale and indications for ICSI and providing an up-to-date discussion on male factor diagnostic tests and microsurgical techniques for ICSI itself. Topics covered include the role of reproductive genetics, the effects of paternal age, the assessment, development and selection of functional human spermatozoa (e.g., Comet assay), both naturally and in the laboratory, and the procedures by which these sperm are injected directly into an oocyte. Comparisons are made between efficacy rates of ICSI versus conventional IVF strategies, and clinical approaches to fertilization failures following ICSI are presented, and intracytoplasmic morphologically selected sperm injection (IMSI) is discussed in detail in a chapter of its own.

Bringing together the latest evidence and written by international leaders in the field, Intracytoplasmic Sperm Injection: Indications, Techniques and Applications is a unique and accessible resource for reproductive endocrinologists, andrologists, geneticists and infertility practitioners and researchers alike.


Assisted reproductive technologies (ART) Azoospermia Cryptozoopermia Comet assay Infertility Intracytoplasmic morphologically selected sperm injection (IMSI) Intracytoplasmic sperm injection (ICSI) In vitro fertilization (IVF) In vitro spermatogenesis Male factor infertility Oligozoospermia Reproductive genetics Sperm DNA integrity Sperm morphology analysis Sperm retrieval methods Spermatogenic dysfunction Spermatozoa Testicular sperm extraction (TESE)

Editors and affiliations

  • Gianpiero D. Palermo
    • 1
  • E. Scott Sills
    • 2
  1. 1.Center for Reproductive MedicineWeill Cornell Medical CollegeNew YorkUSA
  2. 2.Center for Advanced GeneticsSan ClementeUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-70496-8
  • Online ISBN 978-3-319-70497-5
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals