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Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics

  • Ravichandran┬áManisekaran
Book

Part of the Springer Theses book series (Springer Theses)

About this book

Introduction

This thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles.

Keywords

Nanomedicine Nanoparticles for therapeutic purpose Multifunctional nanoflotillas Magnetic and plasmonic nanoparticles Biocompatibility Multimodal imaging Drug delivery and real-time monitoring Core-shell nanoparticles Cancer theranostics Gold nanoparticles

Authors and affiliations

  • Ravichandran┬áManisekaran
    • 1
  1. 1.Center for Research and Advanced Studies of the National Polytechnic InstituteMexico CityMexico

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-67609-8
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Springer, Cham
  • eBook Packages Engineering Engineering (R0)
  • Print ISBN 978-3-319-67608-1
  • Online ISBN 978-3-319-67609-8
  • Series Print ISSN 2190-5053
  • Series Online ISSN 2190-5061
  • Buy this book on publisher's site
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