TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease

  • Adam Telerman
  • Robert Amson

Part of the Results and Problems in Cell Differentiation book series (RESULTS, volume 64)

Table of contents

  1. Front Matter
    Pages i-x
  2. Nadine Assrir, Florian Malard, Ewen Lescop
    Pages 9-46
  3. Beatriz Xoconostle-Cázares, Roberto Ruiz-Medrano
    Pages 47-68
  4. Siting Li, Feng Ge
    Pages 127-136
  5. Léo Betsch, Julie Savarin, Mohammed Bendahmane, Judit Szecsi
    Pages 149-172
  6. Cláudio Gouveia Roque, Christine E. Holt
    Pages 201-215
  7. Jie Zhang, Grace Shim, Sonia M. de Toledo, Edouard I. Azzam
    Pages 227-253
  8. Virginie Baylot, Sara Karaki, Palma Rocchi
    Pages 255-261
  9. Ean-Jeong Seo, Nicolas Fischer, Thomas Efferth
    Pages 263-281
  10. Robert Amson, Christian Auclair, Fabrice André, Judith Karp, Adam Telerman
    Pages 283-290
  11. Back Matter
    Pages 309-309

About this book


This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development. It begins by discussing the structure/function of TCTP, before exploring its role in different species ranging from plants to Drosophila and covering fields such as development, the cytoskeleton, cell division, DNA fragility and apoptosis.

In turn, the book’s final section is devoted to the role of TCTP in disease, namely asthma and diverse cancers, and ultimately as a target for the treatment of malignancies. What is the common denominator between all these processes and why is TCTP necessary in order for them to occur, even in the worst case such as cancer? The book seeks to provide meaningful answers to this and other key questions. Presenting a broad and revealing view on the topic, it offers an informative guide for scientists and students alike.


Translationally Controlled Tumor Protein histamine-releasing factor tumor reversion cell fate cell signalling

Editors and affiliations

  • Adam Telerman
    • 1
  • Robert Amson
    • 2
  1. 1.Bâtiment B2MInstitut Gustave RoussyVillejuifFrance
  2. 2.Bâtiment B2MInstitut Gustave RoussyVillejuifFrance

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-67590-9
  • Online ISBN 978-3-319-67591-6
  • Series Print ISSN 0080-1844
  • Series Online ISSN 1861-0412
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology