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© 2017

A Mathematical Approach to Protein Biophysics

Benefits

  • Exercises included at the end of every chapter

  • Mixes protein biology, mathematics, and computing, supporting a multidisciplinary class

  • Includes detailed notes section and glossary

  • Explains many protein features from a more in-depth perspective

Textbook

Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)

Table of contents

  1. Front Matter
    Pages i-xi
  2. L. Ridgway Scott, Ariel Fernández
    Pages 1-6
  3. L. Ridgway Scott, Ariel Fernández
    Pages 7-29
  4. L. Ridgway Scott, Ariel Fernández
    Pages 31-46
  5. L. Ridgway Scott, Ariel Fernández
    Pages 47-64
  6. L. Ridgway Scott, Ariel Fernández
    Pages 65-84
  7. L. Ridgway Scott, Ariel Fernández
    Pages 85-97
  8. L. Ridgway Scott, Ariel Fernández
    Pages 99-113
  9. L. Ridgway Scott, Ariel Fernández
    Pages 115-136
  10. L. Ridgway Scott, Ariel Fernández
    Pages 137-145
  11. L. Ridgway Scott, Ariel Fernández
    Pages 147-176
  12. L. Ridgway Scott, Ariel Fernández
    Pages 177-190
  13. L. Ridgway Scott, Ariel Fernández
    Pages 191-198
  14. L. Ridgway Scott, Ariel Fernández
    Pages 199-204
  15. L. Ridgway Scott, Ariel Fernández
    Pages 205-212
  16. L. Ridgway Scott, Ariel Fernández
    Pages 213-234
  17. L. Ridgway Scott, Ariel Fernández
    Pages 235-246
  18. L. Ridgway Scott, Ariel Fernández
    Pages 247-250
  19. L. Ridgway Scott, Ariel Fernández
    Pages 251-261
  20. L. Ridgway Scott, Ariel Fernández
    Pages 263-263

About this book

Introduction

This book explores quantitative aspects of protein biophysics and attempts to delineate certain rules of molecular behavior that make atomic scale objects behave in a digital way.  This book will help readers to understand how certain biological systems involving proteins function as digital information systems despite the fact that underlying processes are analog in nature.

The in-depth explanation of proteins from a quantitative point of view and the variety of level of exercises (including physical experiments) at the end of each chapter will appeal to graduate and senior undergraduate students in mathematics, computer science, mechanical engineering, and physics, wanting to learn about the biophysics of proteins.

 L. Ridgway Scott has been Professor of Computer Science and of Mathematics at the University of Chicago since 1998, and the Louis Block Professor since 2001.  He obtained a B.S. degree (Magna Cum Laude) from Tulane University in 1969 and a PhD degree in Mathematics from the Massachusetts Institute of Technology in 1973.  Professor Scott has published over 130 papers and three books, extending over biophysics, parallel computing and fundamental computing aspects of structural mechanics, fluid dynamics, nuclear engineering, and computational chemistry.

Ariel Fernández (born Ariel Fernández Stigliano) is an Argentinian-American physical chemist and mathematician. He obtained his Ph. D. degree in Chemical Physics from Yale University and held the Karl F. Hasselmann Endowed Chair Professorship in Bioengineering at Rice University. He is currently involved in research and entrepreneurial activities at various consultancy firms. Ariel Fernández authored three books on translational medicine and biophysics, and published 360 papers in professional journals. He holds two patents in the field of biotechnology.

Keywords

Protein Biophysics Mathematical Biology Protein Interactivity Continuum Equations Digital Biology Dehydron Wrapping Drug Design Protein Interactions

Authors and affiliations

  1. 1.Departments of Computer Science and Mathematics, Institute for Biophysical Dynamics, Computation InstituteUniversity of ChicagoChicagoUSA
  2. 2.IAM – Argentine Institute of Mathematics, INQUISUR – Chemistry InstituteCONICET – National Research CouncilBuenos AiresArgentina

About the authors

L. Ridgway Scott has been Professor of Computer Science and of Mathematics at the University of Chicago since 1998, and the Louis Block Professor since 2001.  He obtained a B.S. degree (Magna Cum Laude) from Tulane University in 1969 and a PhD degree in Mathematics from the Massachusetts Institute of Technology in 1973.  Professor Scott has published over 130 papers and three books, extending over biophysics, parallel computing and fundamental computing aspects of structural mechanics, fluid dynamics, nuclear engineering, and computational chemistry.

Ariel Fernández (born Ariel Fernández Stigliano) is an Argentinian-American physical chemist and mathematician. He obtained his Ph. D. degree in Chemical Physics from Yale University and held the Karl F. Hasselmann Endowed Chair Professorship in Bioengineering at Rice University. He is currently involved in research and entrepreneurial activities at various consultancy firms. Ariel Fernández authored three books on translational medicine and biophysics, and published 360 papers in professional journals. He holds two patents in the field of biotechnology.

Bibliographic information

Reviews

“The book is built in a textbook-like manner, each chapter being followed by exercises to reinforce the concepts presented throughout. Also included is a comprehensive list of references offering multiple options for future reading. The style of the book makes it accessible to a wide range of audiences from students to established researchers. Although written with a specialised audience in mind, the numerous examples make it accessible to researchers with multidisciplinary backgrounds.” (Irina Ioana Mohorianu, zbMATH 1390.92003, 2018)