Anticoagulant Rodenticides and Wildlife

  • Nico W. van den Brink
  • John E. Elliott
  • Richard F. Shore
  • Barnett A. Rattner

Part of the Emerging Topics in Ecotoxicology book series (ETEP, volume 5)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Nico W. van den Brink, John E. Elliott, Richard F. Shore, Barnett A. Rattner
    Pages 1-9
  3. Katherine E. Horak, Penny M. Fisher, Brian Hopkins
    Pages 87-108
  4. Richard F. Shore, Michaël Coeurdassier
    Pages 135-157
  5. Jhon J. López-Perea, Rafael Mateo
    Pages 159-193
  6. Michaël Coeurdassier, Clémentine Fritsch, Marion Jacquot, Nico W. van den Brink, Patrick Giraudoux
    Pages 195-227
  7. Philippe Berny, Alexandra Esther, Jens Jacob, Colin Prescott
    Pages 259-286
  8. John D. Eisemann, Penny M. Fisher, Alan Buckle, Simon Humphrys
    Pages 287-318
  9. Alan Buckle, Colin Prescott
    Pages 319-355
  10. Nico W. van den Brink, John E. Elliott, Richard F. Shore, Barnett A. Rattner
    Pages 379-386
  11. Back Matter
    Pages 387-398

About this book


Commensal rodents consume and spoil crops and food supplies, cause  property damage and can be vectors for disease. Rats have also invaded islands and can pose a serious threat to native wildlife, particularly seabirds. Estimates of rodent damage range into the billions of dollars in developed countries. In southern Asia, rodents are estimated to consume or destroy annually sufficient rice to feed 50 million people. The predominant control method for pest rodents in most countries is  anticoagulant rodenticides, which are antagonists of vitamin K metabolism that prevent blood-clotting and cause fatal haemorrhage. This mode of toxicity is common to all vertebrates because of their shared blood clotting mechanism, so anticoagulants pose a potential risk to a wide range of non-target species. This is well recognised and anticoagulants fail regulatory environmental risk assessments in many jurisdictions. Nonetheless, the compounds continue to be heavily used because of the societal need for rodent control and the limited availability of safer alternatives.  As a result, exposure of non-target species is commonplace throughout the world and reflects the extensive use, persistence and bioaccumulation potential of many of these compounds. The consequences of such exposure, in terms of effects on wildlife populations, remain uncertain and the subject of much research, debate and controversy.  Accordingly, there is a  significant and ongoing need for integrated assessment of the threats to wildlife from anticoagulant rodenticides, combined with development of governance, mitigation measures and development of alternatives. This book provides a state-of-the-art overview of the scientific advancements in the assessment of exposure, effects and risks that currently used rodenticides may pose to non-target organisms in the environment. This is discussed in relation to their efficacy, and the societal needs for rodent control, and risk mitigation and development of alternatives.


anti-coagulant rodenticides Rodent control Environmental risks control practices Integrated pest management (IPM)

Editors and affiliations

  • Nico W. van den Brink
    • 1
  • John E. Elliott
    • 2
  • Richard F. Shore
    • 3
  • Barnett A. Rattner
    • 4
  1. 1.Division of ToxicologyWageningen UniversityWageningenThe Netherlands
  2. 2.Environment and Climate Change CanadaScience and Technology BranchDeltaCanada
  3. 3.Natural Environment Research CouncilCentre for Ecology and Hydrology, Lancaster Environment CentreLancasterUnited Kingdom
  4. 4.U.S. Geological SurveyPatuxent Wildlife Research CenterBeltsvilleUSA

Bibliographic information

Industry Sectors