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© 2018

Behavioral Pharmacology of Neuropeptides: Oxytocin

  • Rene Hurlemann
  • Valery Grinevich

Benefits

  • Gives insight into a new era of social psychopharmacology based on endogenous neuromodulators

  • Discusses early-life treatment of social-cognitive deficiencies

  • Provides cutting-edge information on "precision medicine"

Book

Part of the Current Topics in Behavioral Neurosciences book series (CTBN, volume 35)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Animal Research Section

    1. Front Matter
      Pages 1-1
    2. Mariela Mitre, Jessica Minder, Egzona X. Morina, Moses V. Chao, Robert C. Froemke
      Pages 31-53
    3. Lars-Lennart Oettl, Wolfgang Kelsch
      Pages 55-75
    4. Gustav F. Jirikowski, Scott D. Ochs, Jack D. Caldwell
      Pages 77-95
    5. Oliver J. Bosch, Larry J. Young
      Pages 97-117
    6. Chihiro Yoshihara, Michael Numan, Kumi O. Kuroda
      Pages 119-153
    7. Catherine Crockford, Tobias Deschner, Roman M. Wittig
      Pages 155-173
    8. Trynke R. de Jong, Inga D. Neumann
      Pages 175-192
    9. Pierrick Poisbeau, Valery Grinevich, Alexandre Charlet
      Pages 193-211
    10. Shlomo Wagner, Hala Harony-Nicolas
      Pages 213-237
    11. Françoise Muscatelli, Michel G. Desarménien, Valery Matarazzo, Valery Grinevich
      Pages 239-268
  3. Human Research Section

    1. Front Matter
      Pages 289-289
    2. C. Sue Carter
      Pages 291-319
    3. Keith M. Kendrick, Adam J. Guastella, Benjamin Becker
      Pages 321-348
    4. Mark A. Ellenbogen
      Pages 349-374
    5. Andreas Ebert, Martin Brüne
      Pages 375-388
    6. Alexandra Patin, Dirk Scheele, Rene Hurlemann
      Pages 389-420

About this book

Introduction

This volume collects cutting-edge expert reviews in the oxytocin field and will be of interest to a broad scientific audience ranging from social neuroscience to clinical psychiatry. The role of the neuropeptide oxytocin in social behaviors is one of the earliest and most significant discoveries in social neuroscience. Influential studies in animal models have delineated many of the neural circuits and genetic components that underlie these behaviors. These discoveries have inspired researchers to investigate the effects of oxytocin on brain and behavior in humans and its potential relevance as a treatment for psychiatric disorders including borderline personality disorder and autism and schizophrenia spectrum disorders. In fact, there is no established social psychopharmacology in Psychiatry, and oxytocin can be seen as the first endogenous agent specifically addressing social-cognitive impairment in psychiatric disorders, with animal research suggesting that it could be especially efficient in the early postnatal period. From a human perspective, it is crucial to understand more precisely who can benefit from potential oxytocin-related treatments, which outcome measures will best represent their effects, how they should be administered, and what brain mechanisms are likely involved in mediating their effects. This type of “precision medicine” approach is in line with the research domain criteria defined by the U.S. National Institute of Mental Health.

Keywords

Oxytocin clinical research preclincal research health and disease intranasal administration

Editors and affiliations

  • Rene Hurlemann
    • 1
  • Valery Grinevich
    • 2
    • 3
  1. 1.Department of PsychiatryUniversity of BonnBonnGermany
  2. 2.Schaller Research Group on Neuropeptides German Cancer Research CenterUniversity of HeidelbergHeidelbergGermany
  3. 3.Central Institute of Mental HealthUniversity of HeidelbergMannheimGermany

Bibliographic information

  • Book Title Behavioral Pharmacology of Neuropeptides: Oxytocin
  • Editors Rene Hurlemann
    Valery Grinevich
  • Series Title Current Topics in Behavioral Neurosciences
  • DOI https://doi.org/10.1007/978-3-319-63739-6
  • Copyright Information Springer International Publishing AG, part of Springer Nature 2018
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-319-63738-9
  • Softcover ISBN 978-3-030-09703-5
  • eBook ISBN 978-3-319-63739-6
  • Series ISSN 1866-3370
  • Series E-ISSN 1866-3389
  • Edition Number 1
  • Number of Pages IX, 593
  • Number of Illustrations 63 b/w illustrations, 37 illustrations in colour
  • Topics Neurosciences
    Psychiatry
    Behavioral Sciences
    Endocrinology
  • Buy this book on publisher's site
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