© 2018

Adrenal Disorders

Physiology, Pathophysiology and Treatment

  • Alice C. Levine


  • A practical, up-to-date clinical text focusing on the structure and function of the adrenal glands and the diagnosis and management of its associated disorders

  • Discusses physiology and pharmacology of the adrenal glands, the genetics and athophysiology of adrenal disorders, and the current diagnosis and management methods used to treat them

  • An excellent resource for clinical endocrinologists as well as endocrine surgeons, pathologists and oncologists


Part of the Contemporary Endocrinology book series (COE)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Physiology

    1. Front Matter
      Pages 1-1
    2. Emanuele Pignatti, Sining Leng, Diana L. Carlone, David T. Breault
      Pages 3-13
    3. Marjut Pihlajoki, Markku Heikinheimo, David B. Wilson
      Pages 15-66
    4. Baha M. Arafah
      Pages 67-81
  3. Genetics and Pathophysiology

    1. Front Matter
      Pages 83-83
    2. Agnieszka Pazderska, Simon H. Pearce, Anna Louise Mitchell
      Pages 85-108
    3. Kazutaka Nanba, Hirotaka Shibata, William E. Rainey
      Pages 129-146
    4. Nada El Ghorayeb, Isabelle Bourdeau, André Lacroix
      Pages 147-171
  4. Diagnosis/Treatment

    1. Front Matter
      Pages 197-197
    2. Xin He, James W. Findling, Richard J. Auchus
      Pages 199-215
    3. Jose Sanchez Escobar, Aarti Ravikumar, Alice C. Levine
      Pages 217-244
    4. William F. Young Jr.
      Pages 245-260
    5. Ivana Jochmanova, Karel Pacak
      Pages 261-310
    6. Silvia De Francia, Paola Perotti, Vittoria Basile, Antonina Germano, Massimo Terzolo
      Pages 311-330
  5. Back Matter
    Pages 331-336

About this book


This practical resource provides the latest evidence, management strategies and recommendations for the treatment of disorders of the adrenal glands, including related physiology, genetics and pharmacology. This book is divided into three thematic sections. The first covers adrenal physiology, presenting adrenal zonation and development, the regulation of steroidogenesis, and the pharmacology of glucocortisoids. Part two discusses the genetics and pathophysiology of a number of adrenal disorders, including autoimmune Addison’s disease, congenital adrenal hyperplasia, primary aldosteronism, adrenocortical tumors and hyperplasias, and pheochromocytomas and paragangliomas. The final section presents the latest diagnostic and management strategies for these disorders, addressing adrenal insufficiency, adrenal Cushing’s Syndrome and aldosteronism, among others.

Over the past twenty years, our understanding of disorders of the adrenal glands has been altered and deepened. Providing a much-needed update to the literature, Adrenal Disorders: Physiology, Pathophysiology and Treatment will be an important resource for both academic and clinical endocrinologists working with the adrenal glands and managing patients with adrenal disorders.


Addison's disease Adrenal cortical carcinoma Adrenal gland Adrenal insufficiency Adrenal medulla Adrenal zonation Congenital adrenal hyperplasia Cushing's syndrome Glucocortocoids Pheochromocytoma Primary aldosteronism Paraganglioma Steroidogenesis

Editors and affiliations

  • Alice C. Levine
    • 1
  1. 1.Div of Endocrinology and Bone DiseasesIcahn School of Medicine at Mount SinaiNew YorkUSA

About the editors

Alice C. Levine, MD, Icahn School of Medicine at Mount Sinai, Department of Medicine - Endocrinology, New York, NY, USA

Bibliographic information

  • Book Title Adrenal Disorders
  • Book Subtitle Physiology, Pathophysiology and Treatment
  • Editors Alice C. Levine
  • Series Title Contemporary Endocrinology
  • Series Abbreviated Title Contemporary Endocrinology
  • DOI
  • Copyright Information Springer International Publishing AG 2018
  • Publisher Name Humana Press, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-62469-3
  • Softcover ISBN 978-3-319-87320-6
  • eBook ISBN 978-3-319-62470-9
  • Series ISSN 2523-3785
  • Series E-ISSN 2523-3793
  • Edition Number 1
  • Number of Pages XIII, 336
  • Number of Illustrations 10 b/w illustrations, 38 illustrations in colour
  • Topics Endocrinology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology