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Viruses, Genes, and Cancer

  • Eric Hunter
  • Klaus Bister

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 407)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Daniela C. Monaco, Zachary Ende, Eric Hunter
    Pages 31-63
  3. Ronald Swanstrom, William D. Graham, Shuntai Zhou
    Pages 65-82
  4. Masahiro Aoki, Teruaki Fujishita
    Pages 153-189

About this book

Introduction

This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.

Keywords

Virus-host cell interactions Oncogenic signaling MYC RAF PI3 kinase mTOR MicroRNA Tumor suppressors P53 gene

Editors and affiliations

  • Eric Hunter
    • 1
  • Klaus Bister
    • 2
  1. 1.Emory Vaccine CenterEmory UniversityAtlantaUSA
  2. 2.Institute of Biochemistry and Center for Molecular BiosciencesUniversity of InnsbruckInnsbruckAustria

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-61804-3
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-61803-6
  • Online ISBN 978-3-319-61804-3
  • Series Print ISSN 0070-217X
  • Series Online ISSN 2196-9965
  • Buy this book on publisher's site
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