© 2018


The EMBARC Manual

  • James Chalmers
  • Eva Polverino
  • Stefano Aliberti

Table of contents

  1. Front Matter
    Pages i-viii
  2. Robert Wilson
    Pages 1-8
  3. Mario Silva, Gianluca Milanese, Nicola Sverzellati
    Pages 9-26
  4. Montserrat Vendrell, Dušanka Obradović, Roland Diel, Javier de Gracia
    Pages 27-37
  5. Diego J. Maselli, Marcos I. Restrepo
    Pages 39-49
  6. Rosario Menéndez, Oriol Sibila
    Pages 51-64
  7. Andrea Gramegna, Francesco Amati, James D. Chalmers, Stuart J. Elborn, Stefano Aliberti, Francesco Blasi
    Pages 65-76
  8. Tanya I. Coulter, Lisa Devlin, Damian Downey, J. Stuart Elborn, J. David M. Edgar
    Pages 77-100
  9. Anna Nogués Sabaté, José María Guilemany Toste
    Pages 101-106
  10. Miguel Angel Martínez-Garcia, Katerina Dimakou
    Pages 107-127
  11. Melissa J. McDonnell, Robert M. Rutherford
    Pages 129-145
  12. Tom M. Quinn, Adam T. Hill
    Pages 147-155
  13. Anthony De Soyza, Craig Winstanley
    Pages 157-180
  14. Michael R. Loebinger, Timothy Aksamit
    Pages 189-204
  15. Eva Polverino, Edmundo Rosales-Mayor, Antoni Torres
    Pages 205-222
  16. Michal Shteinberg, Chris Johnson, Charles Haworth
    Pages 223-239
  17. Pieter Christian Goeminne, Menno Van der Eerden
    Pages 241-256
  18. Judy Bradley, Katherine O’Neill, Jordi Vilaró, Maggie McIlwaine
    Pages 257-284
  19. Annemarie L. Lee, Anne E. Holland
    Pages 285-305

About this book


This book presents state of the art knowledge and practice in the rapidly developing field of bronchiectasis not due to cystic fibrosis (referred to below simply as bronchiectasis). The focus is especially on diagnosis and existing and emerging therapies, but the book also covers a wide range of other key topics, from pathophysiology, histopathology, and immunology through to pulmonary rehabilitation, nursing care, and management in primary care and pediatric settings.

While bronchiectasis was formerly regarded as an “orphan” disease, international data reveal an increase in its prevalence in recent years. Accordingly, there has been renewed interest in the disease, resulting in more clinical research and the development of new treatments. The impact of bronchiectasis on healthcare systems is substantial and it has a clear attributable mortality. In covering all aspects of the disease, this book will be of interest to respiratory, internal medicine, and infectious disease fellows and specialists, final-year medical students, and nurses and physiotherapists. The authors are leading experts and chairs of the steering committee of EMBARC, the first truly international bronchiectasis network. 


Airway disease Microbiology Inhaled antibiotics Chronic infection Recurrent respiratory infections Oral antibiotics Pulmonary rehabilitation Predisposing factors Airway clearance Nursing management

Editors and affiliations

  • James Chalmers
    • 1
  • Eva Polverino
    • 2
  • Stefano Aliberti
    • 3
  1. 1.College of MedicineUniversity of Dundee DundeeUnited Kingdom
  2. 2.Hospital Vall D’HebronVall D’Hebron Research Institute (VHIR) Respiratory Disease DepartmentBarcelonaSpain
  3. 3.Department of Pathophysiology and Transplantation, University of Milan Internal Medicine DepartmentRespiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore PoliclinicoMilanItaly

About the editors

Dr James D Chalmers is Senior Clinical Lecturer and Consultant Physician at the Scottish Centre for Respiratory Research at the University of Dundee. He runs a large specialist bronchiectasis clinic in the East of Scotland and a research group focussing on the interactions between neutrophil mediated inflammation and bacterial infection in chronic respiratory disease, particularly bronchiectasis and COPD. He is associated editor of the European Respiratory Journal and a member of the international advisory board of the Lancet Respiratory Medicine. He is chair of the European Bronchiectasis Network and Registry (EMBARC). 

Eva Polverino is Doctor of Medicine in Cardiopulmonary Pathophysiology from the University of Pisa (Italy). She currently works as postdoctoral clinical researcher at the Hospital Clinic in Barcelona, IDIBAPS. Specialist in respiratory medicine, she is involved in the field of respiratory infections and particularly in Community Acquired Pneumonia (CAP), noncystic fibrosis bronchiectasis (NCFB) and humoral immuno-deficiencies. She investigates epidemiology, risk factors, outcome, treatment and prevention of the most relevant respiratory infections. In the field of bronchiectasis main objectives are focused on investigation of the prevalence and outcomes of this underestimated but very frequent disease, and its impact on the society. The results of her research are aimed at investigating pathogenetic mechanisms of respiratory infections, improving their clinical outcomes and patients’ quality of life.

Stefano Aliberti is Associate Professor of Respiratory Medicine at the University of Milan and consultant at the Cardio-Thoracic Unit and Cystic Fibrosis Adult Center at the Policlinico Hospital in Milan, Italy. His research interest is in respiratory infectious diseases, including bronchiectasis, NTM and pneumonia. He has published extensively in this area over the past 10 years as well as co-authoring books and book chapters on respiratory medicine. He is Head of the Respiratory Infection Assembly of the European Respiratory Society. He is chair of EMBARC (European Multicentre Bronchiectasis Audit and Research Collaboration), director of the Italian Registry of Bronchiectasis IRIDE and the Italian Registry of pulmonary NTM IRENE.

Bibliographic information

Industry Sectors
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Internal Medicine & Dermatology


“This is excellently written book provides an up-to-date and concise summary of our current understanding of bronchiectasis as well as highlighting gaps in our knowledge and where we should target research efforts in the future. … This is book will provide a valuable reference for health-care professionals looking for succinct, up-to-date information to help them holistically investigate and manage their patients with bronchiectasis.” (J.K. Quin, British Journal of Hospital Medicine, Vol. 79 (6), June, 2018)

“This is a very useful book on the causes, diagnosis, and management of bronchiectasis not due to cystic fibrosis with an emphasis on the role of chronic infections in disease progression. This should be a welcome addition to the library of every pulmonologist who takes care of patients with this difficult disease.” (Santosh Dhungana, Doody's Book Reviews, May, 2018)